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Sept8/SEPTIN8 involvement in cellular structure and kidney damage is identified by genetic mapping and a novel human tubule hypoxic model.
Keele GR, Prokop JW, He H, Holl K, Littrell J, Deal AW, Kim Y, Kyle PB, Attipoe E, Johnson AC, Uhl KL, Sirpilla OL, Jahanbakhsh S, Robinson M, Levy S, Valdar W, Garrett MR, Solberg Woods LC. Keele GR, et al. Among authors: valdar w. Sci Rep. 2021 Jan 22;11(1):2071. doi: 10.1038/s41598-021-81550-8. Sci Rep. 2021. PMID: 33483609 Free PMC article.
Genetic Fine-Mapping and Identification of Candidate Genes and Variants for Adiposity Traits in Outbred Rats.
Keele GR, Prokop JW, He H, Holl K, Littrell J, Deal A, Francic S, Cui L, Gatti DM, Broman KW, Tschannen M, Tsaih SW, Zagloul M, Kim Y, Baur B, Fox J, Robinson M, Levy S, Flister MJ, Mott R, Valdar W, Solberg Woods LC. Keele GR, et al. Among authors: valdar w. Obesity (Silver Spring). 2018 Jan;26(1):213-222. doi: 10.1002/oby.22075. Epub 2017 Nov 28. Obesity (Silver Spring). 2018. PMID: 29193816 Free PMC article.
Transcriptome-wide analyses of adipose tissue in outbred rats reveal genetic regulatory mechanisms relevant for human obesity.
Crouse WL, Das SK, Le T, Keele G, Holl K, Seshie O, Craddock AL, Sharma NK, Comeau ME, Langefeld CD, Hawkins GA, Mott R, Valdar W, Solberg Woods LC. Crouse WL, et al. Among authors: valdar w. Physiol Genomics. 2022 Jun 1;54(6):206-219. doi: 10.1152/physiolgenomics.00172.2021. Epub 2022 Apr 25. Physiol Genomics. 2022. PMID: 35467982 Free PMC article.
Genetic Mapping of Multiple Traits Identifies Novel Genes for Adiposity, Lipids, and Insulin Secretory Capacity in Outbred Rats.
Hong-Le T, Crouse WL, Keele GR, Holl K, Seshie O, Tschannen M, Craddock A, Das SK, Szalanczy AM, McDonald B, Grzybowski M, Klotz J, Sharma NK, Geurts AM, Key CC, Hawkins G, Valdar W, Mott R, Solberg Woods LC. Hong-Le T, et al. Among authors: valdar w. Diabetes. 2023 Jan 1;72(1):135-148. doi: 10.2337/db22-0252. Diabetes. 2023. PMID: 36219827 Free PMC article.
A Bayesian model selection approach to mediation analysis.
Crouse WL, Keele GR, Gastonguay MS, Churchill GA, Valdar W. Crouse WL, et al. Among authors: valdar w. PLoS Genet. 2022 May 9;18(5):e1010184. doi: 10.1371/journal.pgen.1010184. eCollection 2022 May. PLoS Genet. 2022. PMID: 35533209 Free PMC article.
91 results