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A heterologous prime-boost strategy for immunization against Dengue virus combining the Tetra DIIIC subunit vaccine candidate with the TV005 live-attenuated tetravalent vaccine.
Valdés I, Izquierdo A, Cobas K, Thao P, Anh Duc H, Duc Loc H, Dung LT, Lazo L, Suzarte E, Pérez Y, Romero Y, Yaugel M, Marcos E, Guzmán MG, Dat DT, Hien ND, Guillén G, Gil L, Hermida L. Valdés I, et al. J Gen Virol. 2019 Jun;100(6):975-984. doi: 10.1099/jgv.0.001271. Epub 2019 May 15. J Gen Virol. 2019. PMID: 31090533
A fragment of the envelope protein from dengue-1 virus, fused in two different sites of the meningococcal P64k protein carrier, induces a functional immune response in mice.
Hermida L, Rodríguez R, Lazo L, Bernardo L, Silva R, Zulueta A, López C, Martín J, Valdés I, del Rosario D, Guillén G, Guzmán MG. Hermida L, et al. Among authors: valdes i. Biotechnol Appl Biochem. 2004 Feb;39(Pt 1):107-14. doi: 10.1042/BA20030039. Biotechnol Appl Biochem. 2004. PMID: 12887334
The fusion site of envelope fragments from each serotype of Dengue virus in the P64k protein, influence some parameters of the resulting chimeric constructs.
Zulueta A, Hermida L, Lazo L, Valdés I, Rodríguez R, López C, Silva R, Rosario D, Martín J, Guzmán MG, Guillén G. Zulueta A, et al. Among authors: valdes i. Biochem Biophys Res Commun. 2003 Aug 29;308(3):619-26. doi: 10.1016/s0006-291x(03)01411-6. Biochem Biophys Res Commun. 2003. PMID: 12914796
Immunological evaluation in nonhuman primates of formulations based on the chimeric protein P64k-domain III of dengue 2 and two components of Neisseria meningitidis.
Valdés I, Hermida L, Martín J, Menéndez T, Gil L, Lazo L, Castro J, Niebla O, López C, Bernardo L, Sánchez J, Romero Y, Martínez R, Guzmán MG, Guillén G. Valdés I, et al. Vaccine. 2009 Feb 11;27(7):995-1001. doi: 10.1016/j.vaccine.2008.11.106. Epub 2008 Dec 25. Vaccine. 2009. PMID: 19100804
101 results