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Enhanced triacylglycerol catabolism by carboxylesterase 1 promotes aggressive colorectal carcinoma.
Capece D, D'Andrea D, Begalli F, Goracci L, Tornatore L, Alexander JL, Di Veroli A, Leow SC, Vaiyapuri TS, Ellis JK, Verzella D, Bennett J, Savino L, Ma Y, McKenzie JS, Doria ML, Mason SE, Chng KR, Keun HC, Frost G, Tergaonkar V, Broniowska K, Stunkel W, Takats Z, Kinross JM, Cruciani G, Franzoso G. Capece D, et al. Among authors: vaiyapuri ts. J Clin Invest. 2021 Jun 1;131(11):e137845. doi: 10.1172/JCI137845. J Clin Invest. 2021. PMID: 33878036 Free PMC article.
p53-NEIL1 co-abnormalities induce genomic instability and promote synthetic lethality with Chk1 inhibition in multiple myeloma having concomitant 17p13(del) and 1q21(gain).
Teoh PJ, An O, Chung TH, Vaiyapuri T, Raju A, Hoppe MM, Toh SHM, Wang W, Chan MC, Fullwood MJ, Jeyasekharan AD, Tergaonkar V, Chen L, Yang H, Chng WJ. Teoh PJ, et al. Oncogene. 2022 Apr;41(14):2106-2121. doi: 10.1038/s41388-022-02227-8. Epub 2022 Feb 21. Oncogene. 2022. PMID: 35190641
Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis.
Zhang J, Hu Z, Chung HH, Tian Y, Lau KW, Ser Z, Lim YT, Sobota RM, Leong HF, Chen BJ, Yeo CJ, Tan SYX, Kang J, Tan DEK, Sou IF, McClurg UL, Lakshmanan M, Vaiyapuri TS, Raju A, Wong ESM, Tergaonkar V, Rajarethinam R, Pathak E, Tam WL, Tan EY, Tee WW. Zhang J, et al. Among authors: vaiyapuri ts. Nat Commun. 2023 Apr 28;14(1):2439. doi: 10.1038/s41467-023-38132-1. Nat Commun. 2023. PMID: 37117180 Free PMC article.
Synthesis and pharmacological evaluation of novel N-aryl-3,4-dihydro-1'H-spiro[chromene-2,4'-piperidine]-1'-carboxamides as TRPM8 antagonists.
Chaudhari SS, Kadam AB, Khairatkar-Joshi N, Mukhopadhyay I, Karnik PV, Raghuram A, Rao SS, Vaiyapuri TS, Wale DP, Bhosale VM, Gudi GS, Sangana RR, Thomas A. Chaudhari SS, et al. Among authors: vaiyapuri ts. Bioorg Med Chem. 2013 Nov 1;21(21):6542-53. doi: 10.1016/j.bmc.2013.08.031. Epub 2013 Aug 29. Bioorg Med Chem. 2013. PMID: 24055075