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An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease.
Ruotsalainen SE, Partanen JJ, Cichonska A, Lin J, Benner C, Surakka I; FinnGen; Reeve MP, Palta P, Salmi M, Jalkanen S, Ahola-Olli A, Palotie A, Salomaa V, Daly MJ, Pirinen M, Ripatti S, Koskela J. Ruotsalainen SE, et al. Eur J Hum Genet. 2021 Feb;29(2):309-324. doi: 10.1038/s41431-020-00730-8. Epub 2020 Oct 27. Eur J Hum Genet. 2021. PMID: 33110245 Free PMC article.
Calcium signaling induces partial EMT and renal fibrosis in a Wnt4mCherry knock-in mouse model.
Naillat F, Deshar G, Hankkila A, Rak-Raszewska A, Sharma A, Prunskaite-Hyyrylainen R, Railo A, Shan J, Vainio SJ. Naillat F, et al. Among authors: vainio sj. Biochim Biophys Acta Mol Basis Dis. 2024 Apr 21;1870(5):167180. doi: 10.1016/j.bbadis.2024.167180. Online ahead of print. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38653356 Free article.
Translatome profiling reveals Itih4 as a novel smooth muscle cell-specific gene in atherosclerosis.
Ravindran A, Holappa L, Niskanen H, Skovorodkin I, Kaisto S, Beter M, Kiema M, Selvarajan I, Nurminen V, Aavik E, Aherrahrou R, Pasonen-Seppänen S, Fortino V, Laakkonen JP, Ylä-Herttuala S, Vainio S, Örd T, Kaikkonen MU. Ravindran A, et al. Among authors: vainio s. Cardiovasc Res. 2024 Jan 30:cvae028. doi: 10.1093/cvr/cvae028. Online ahead of print. Cardiovasc Res. 2024. PMID: 38289873
Enrichment of sweat-derived extracellular vesicles of human and bacterial origin for biomarker identification.
Zhyvolozhnyi A, Samoylenko A, Bart G, Kaisanlahti A, Hekkala J, Makieieva O, Pratiwi F, Miinalainen I, Kaakinen M, Bergman U, Singh P, Nurmi T, Khosrowbadi E, Abdelrady E, Kellokumpu S, Kosamo S, Reunanen J, Röning J, Hiltunen J, Vainio SJ. Zhyvolozhnyi A, et al. Among authors: vainio sj. Nanotheranostics. 2024 Jan 1;8(1):48-63. doi: 10.7150/ntno.87822. eCollection 2024. Nanotheranostics. 2024. PMID: 38164498 Free PMC article.
Maternal microbiota communicates with the fetus through microbiota-derived extracellular vesicles.
Kaisanlahti A, Turunen J, Byts N, Samoylenko A, Bart G, Virtanen N, Tejesvi MV, Zhyvolozhnyi A, Sarfraz S, Kumpula S, Hekkala J, Salmi S, Will O, Korvala J, Paalanne N, Erawijantari PP, Suokas M, Medina TP, Vainio S, Medina OP, Lahti L, Tapiainen T, Reunanen J. Kaisanlahti A, et al. Among authors: vainio s. Microbiome. 2023 Nov 13;11(1):249. doi: 10.1186/s40168-023-01694-9. Microbiome. 2023. PMID: 37953319 Free PMC article.
Metformin increases the uptake of glucose into the gut from the circulation in high-fat diet-fed male mice, which is enhanced by a reduction in whole-body Slc2a2 expression.
Morrice N, Vainio S, Mikkola K, van Aalten L, Gallagher JR, Ashford MLJ, McNeilly AD, McCrimmon RJ, Grosfeld A, Serradas P, Koffert J, Pearson ER, Nuutila P, Sutherland C. Morrice N, et al. Among authors: vainio s. Mol Metab. 2023 Nov;77:101807. doi: 10.1016/j.molmet.2023.101807. Epub 2023 Sep 16. Mol Metab. 2023. PMID: 37717665 Free PMC article.
231 results