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6 results
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Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities.
Nat Commun. 2018 Dec 21;9(1):5416. doi: 10.1038/s41467-018-07901-8.
Nat Commun. 2018.
PMID: 30575746
Free PMC article.
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.
Doench JG, Fusi N, Sullender M, Hegde M, Vaimberg EW, Donovan KF, Smith I, Tothova Z, Wilen C, Orchard R, Virgin HW, Listgarten J, Root DE.
Doench JG, et al. Among authors: vaimberg ew.
Nat Biotechnol. 2016 Feb;34(2):184-191. doi: 10.1038/nbt.3437. Epub 2016 Jan 18.
Nat Biotechnol. 2016.
PMID: 26780180
Free PMC article.
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Creation of Novel Protein Variants with CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product into a Discovery Tool.
Donovan KF, Hegde M, Sullender M, Vaimberg EW, Johannessen CM, Root DE, Doench JG.
Donovan KF, et al. Among authors: vaimberg ew.
PLoS One. 2017 Jan 24;12(1):e0170445. doi: 10.1371/journal.pone.0170445. eCollection 2017.
PLoS One. 2017.
PMID: 28118392
Free PMC article.
Item in Clipboard
Orthologous CRISPR-Cas9 enzymes for combinatorial genetic screens.
Najm FJ, Strand C, Donovan KF, Hegde M, Sanson KR, Vaimberg EW, Sullender ME, Hartenian E, Kalani Z, Fusi N, Listgarten J, Younger ST, Bernstein BE, Root DE, Doench JG.
Najm FJ, et al. Among authors: vaimberg ew.
Nat Biotechnol. 2018 Feb;36(2):179-189. doi: 10.1038/nbt.4048. Epub 2017 Dec 18.
Nat Biotechnol. 2018.
PMID: 29251726
Free PMC article.
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Systematic identification of biomarker-driven drug combinations to overcome resistance.
Rees MG, Brenan L, do Carmo M, Duggan P, Bajrami B, Arciprete M, Boghossian A, Vaimberg E, Ferrara SJ, Lewis TA, Rosenberg D, Sangpo T, Roth JA, Kaushik VK, Piccioni F, Doench JG, Root DE, Johannessen CM.
Rees MG, et al.
Nat Chem Biol. 2022 Jun;18(6):615-624. doi: 10.1038/s41589-022-00996-7. Epub 2022 Mar 24.
Nat Chem Biol. 2022.
PMID: 35332332
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Project Inclusive Genetics: Exploring the impact of patient-centered counseling training on physical disability bias in the prenatal setting.
Vaimberg E, Demers L, Ford E, Sabatello M, Stevens B, Dasgupta S.
Vaimberg E, et al.
PLoS One. 2021 Aug 5;16(8):e0255722. doi: 10.1371/journal.pone.0255722. eCollection 2021.
PLoS One. 2021.
PMID: 34352009
Free PMC article.
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