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TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision.
Chen Z, Ji Z, Ngiow SF, Manne S, Cai Z, Huang AC, Johnson J, Staupe RP, Bengsch B, Xu C, Yu S, Kurachi M, Herati RS, Vella LA, Baxter AE, Wu JE, Khan O, Beltra JC, Giles JR, Stelekati E, McLane LM, Lau CW, Yang X, Berger SL, Vahedi G, Ji H, Wherry EJ. Chen Z, et al. Among authors: vahedi g. Immunity. 2019 Nov 19;51(5):840-855.e5. doi: 10.1016/j.immuni.2019.09.013. Epub 2019 Oct 9. Immunity. 2019. PMID: 31606264 Free PMC article.
Early Th1 cell differentiation is marked by a Tfh cell-like transition.
Nakayamada S, Kanno Y, Takahashi H, Jankovic D, Lu KT, Johnson TA, Sun HW, Vahedi G, Hakim O, Handon R, Schwartzberg PL, Hager GL, O'Shea JJ. Nakayamada S, et al. Among authors: vahedi g. Immunity. 2011 Dec 23;35(6):919-31. doi: 10.1016/j.immuni.2011.11.012. Immunity. 2011. PMID: 22195747 Free PMC article.
Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity.
Hirahara K, Onodera A, Villarino AV, Bonelli M, Sciumè G, Laurence A, Sun HW, Brooks SR, Vahedi G, Shih HY, Gutierrez-Cruz G, Iwata S, Suzuki R, Mikami Y, Okamoto Y, Nakayama T, Holland SM, Hunter CA, Kanno Y, O'Shea JJ. Hirahara K, et al. Among authors: vahedi g. Immunity. 2015 May 19;42(5):877-89. doi: 10.1016/j.immuni.2015.04.014. Immunity. 2015. PMID: 25992861 Free PMC article.
Enhancing our understanding of enhancers in T-helper cells.
Paiano JJ, Johnson JL, Vahedi G. Paiano JJ, et al. Among authors: vahedi g. Eur J Immunol. 2015 Nov;45(11):2998-3001. doi: 10.1002/eji.201546035. Epub 2015 Oct 20. Eur J Immunol. 2015. PMID: 26444855 Free PMC article.
Exploiting Chromatin Biology to Understand Immunology.
Johnson JL, Vahedi G. Johnson JL, et al. Among authors: vahedi g. Methods Enzymol. 2016;574:365-383. doi: 10.1016/bs.mie.2016.03.016. Epub 2016 Apr 27. Methods Enzymol. 2016. PMID: 27423869
Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade.
Pauken KE, Sammons MA, Odorizzi PM, Manne S, Godec J, Khan O, Drake AM, Chen Z, Sen DR, Kurachi M, Barnitz RA, Bartman C, Bengsch B, Huang AC, Schenkel JM, Vahedi G, Haining WN, Berger SL, Wherry EJ. Pauken KE, et al. Among authors: vahedi g. Science. 2016 Dec 2;354(6316):1160-1165. doi: 10.1126/science.aaf2807. Epub 2016 Oct 27. Science. 2016. PMID: 27789795 Free PMC article.
99 results