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Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation.
Samadder P, Suchánková T, Hylse O, Khirsariya P, Nikulenkov F, Drápela S, Straková N, Vaňhara P, Vašíčková K, Kolářová H, Binó L, Bittová M, Ovesná P, Kollár P, Fedr R, Ešner M, Jaroš J, Hampl A, Krejčí L, Paruch K, Souček K. Samadder P, et al. Among authors: vasickova k. Mol Cancer Ther. 2017 Sep;16(9):1831-1842. doi: 10.1158/1535-7163.MCT-17-0018. Epub 2017 Jun 15. Mol Cancer Ther. 2017. PMID: 28619751
TUSC3: functional duality of a cancer gene.
Vašíčková K, Horak P, Vaňhara P. Vašíčková K, et al. Cell Mol Life Sci. 2018 Mar;75(5):849-857. doi: 10.1007/s00018-017-2660-4. Epub 2017 Sep 19. Cell Mol Life Sci. 2018. PMID: 28929175 Review.
Casein kinase 1 is a therapeutic target in chronic lymphocytic leukemia.
Janovska P, Verner J, Kohoutek J, Bryjova L, Gregorova M, Dzimkova M, Skabrahova H, Radaszkiewicz T, Ovesna P, Vondalova Blanarova O, Nemcova T, Hoferova Z, Vasickova K, Smyckova L, Egle A, Pavlova S, Poppova L, Plevova K, Pospisilova S, Bryja V. Janovska P, et al. Among authors: vasickova k. Blood. 2018 Mar 15;131(11):1206-1218. doi: 10.1182/blood-2017-05-786947. Epub 2018 Jan 9. Blood. 2018. PMID: 29317454 Free article.
A metabolic switch in proteasome inhibitor-resistant multiple myeloma ensures higher mitochondrial metabolism, protein folding and sphingomyelin synthesis.
Besse L, Besse A, Mendez-Lopez M, Vasickova K, Sedlackova M, Vanhara P, Kraus M, Bader J, Ferreira RB, Castellano RK, Law BK, Driessen C. Besse L, et al. Among authors: vasickova k. Haematologica. 2019 Sep;104(9):e415-e419. doi: 10.3324/haematol.2018.207704. Epub 2019 Feb 21. Haematologica. 2019. PMID: 30792209 Free PMC article. No abstract available.
Apoferritin as an ubiquitous nanocarrier with excellent shelf life.
Dostalova S, Vasickova K, Hynek D, Krizkova S, Richtera L, Vaculovicova M, Eckschlager T, Stiborova M, Heger Z, Adam V. Dostalova S, et al. Among authors: vasickova k. Int J Nanomedicine. 2017 Mar 24;12:2265-2278. doi: 10.2147/IJN.S130267. eCollection 2017. Int J Nanomedicine. 2017. PMID: 28392686 Free PMC article.
11 results