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Genomic structural variations lead to dysregulation of important coding and non-coding RNA species in dilated cardiomyopathy.
Haas J, Mester S, Lai A, Frese KS, Sedaghat-Hamedani F, Kayvanpour E, Rausch T, Nietsch R, Boeckel JN, Carstensen A, Völkers M, Dietrich C, Pils D, Amr A, Holzer DB, Martins Bordalo D, Oehler D, Weis T, Mereles D, Buss S, Riechert E, Wirsz E, Wuerstle M, Korbel JO, Keller A, Katus HA, Posch AE, Meder B. Haas J, et al. Among authors: volkers m. EMBO Mol Med. 2018 Jan;10(1):107-120. doi: 10.15252/emmm.201707838. EMBO Mol Med. 2018. PMID: 29138229 Free PMC article.
Hope for a broken heart?
Most P, Eicher C, Völkers M, Pleger ST, Katus HA. Most P, et al. Among authors: volkers m. Trends Biotechnol. 2004 Oct;22(10):487-9. doi: 10.1016/j.tibtech.2004.08.004. Trends Biotechnol. 2004. PMID: 15450736
S100A1 is released from ischemic cardiomyocytes and signals myocardial damage via Toll-like receptor 4.
Rohde D, Schön C, Boerries M, Didrihsone I, Ritterhoff J, Kubatzky KF, Völkers M, Herzog N, Mähler M, Tsoporis JN, Parker TG, Linke B, Giannitsis E, Gao E, Peppel K, Katus HA, Most P. Rohde D, et al. Among authors: volkers m. EMBO Mol Med. 2014 Jun;6(6):778-94. doi: 10.15252/emmm.201303498. Epub 2014 Apr 6. EMBO Mol Med. 2014. PMID: 24833748 Free PMC article.
A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway.
Lehmann LH, Jebessa ZH, Kreusser MM, Horsch A, He T, Kronlage M, Dewenter M, Sramek V, Oehl U, Krebs-Haupenthal J, von der Lieth AH, Schmidt A, Sun Q, Ritterhoff J, Finke D, Völkers M, Jungmann A, Sauer SW, Thiel C, Nickel A, Kohlhaas M, Schäfer M, Sticht C, Maack C, Gretz N, Wagner M, El-Armouche A, Maier LS, Londoño JEC, Meder B, Freichel M, Gröne HJ, Most P, Müller OJ, Herzig S, Furlong EEM, Katus HA, Backs J. Lehmann LH, et al. Among authors: volkers m. Nat Med. 2018 Jan;24(1):62-72. doi: 10.1038/nm.4452. Epub 2017 Dec 11. Nat Med. 2018. PMID: 29227474
89 results