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First homology model of Plasmodium falciparum glucose-6-phosphate dehydrogenase: Discovery of selective substrate analog-based inhibitors as novel antimalarial agents.
Alencar N, Sola I, Linares M, Juárez-Jiménez J, Pont C, Viayna A, Vílchez D, Sampedro C, Abad P, Pérez-Benavente S, Lameira J, Bautista JM, Muñoz-Torrero D, Luque FJ. Alencar N, et al. Among authors: vilchez d. Eur J Med Chem. 2018 Feb 25;146:108-122. doi: 10.1016/j.ejmech.2018.01.044. Epub 2018 Feb 4. Eur J Med Chem. 2018. PMID: 29407943
Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV-1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety Profiles.
Huang B, Chen W, Zhao T, Li Z, Jiang X, Ginex T, Vílchez D, Luque FJ, Kang D, Gao P, Zhang J, Tian Y, Daelemans D, De Clercq E, Pannecouque C, Zhan P, Liu X. Huang B, et al. Among authors: vilchez d. J Med Chem. 2019 Feb 28;62(4):2083-2098. doi: 10.1021/acs.jmedchem.8b01729. Epub 2019 Feb 20. J Med Chem. 2019. PMID: 30721060
In planta expression of human polyQ-expanded huntingtin fragment reveals mechanisms to prevent disease-related protein aggregation.
Llamas E, Koyuncu S, Lee HJ, Wehrmann M, Gutierrez-Garcia R, Dunken N, Charura N, Torres-Montilla S, Schlimgen E, Mandel AM, Theile EB, Grossbach J, Wagle P, Lackmann JW, Schermer B, Benzing T, Beyer A, Pulido P, Rodriguez-Concepcion M, Zuccaro A, Vilchez D. Llamas E, et al. Among authors: vilchez d. Nat Aging. 2023 Nov;3(11):1345-1357. doi: 10.1038/s43587-023-00502-1. Epub 2023 Oct 2. Nat Aging. 2023. PMID: 37783816 Free PMC article.
Arabidopsis metacaspase MC1 localizes in stress granules, clears protein aggregates, and delays senescence.
Ruiz-Solaní N, Salguero-Linares J, Armengot L, Santos J, Pallarès I, van Midden KP, Phukkan UJ, Koyuncu S, Borràs-Bisa J, Li L, Popa C, Eisele F, Eisele-Bürger AM, Hill SM, Gutiérrez-Beltrán E, Nyström T, Valls M, Llamas E, Vilchez D, Klemenčič M, Ventura S, Coll NS. Ruiz-Solaní N, et al. Among authors: vilchez d. Plant Cell. 2023 Sep 1;35(9):3325-3344. doi: 10.1093/plcell/koad172. Plant Cell. 2023. PMID: 37401663 Free PMC article.
Experiences of insecurity among non-standard workers across different welfare states: A qualitative cross-country study.
Bosmans K, Vignola EF, Álvarez-López V, Julià M, Ahonen EQ, Bolíbar M, Gutiérrez-Zamora M, Ivarsson L, Kvart S, Muntaner C, O'Campo P, Ruiz ME, Vänerhagen K, Cuervo I, Davis L, Diaz I, Escrig-Piñol A, Gunn V, Lewchuk W, Östergren PO, Padrosa E, Vílchez D, Vives A, Vos M, Zaupa A, Bodin T, Baron SL. Bosmans K, et al. Among authors: vilchez d. Soc Sci Med. 2023 Jun;327:115970. doi: 10.1016/j.socscimed.2023.115970. Epub 2023 May 17. Soc Sci Med. 2023. PMID: 37210981 Free article.
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