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Recent Advances in Practical Methods for Liver Cell Biology: A Short Overview.
Torres S, Abdullah Z, Brol MJ, Hellerbrand C, Fernandez M, Fiorotto R, Klein S, Königshofer P, Liedtke C, Lotersztajn S, Nevzorova YA, Schierwagen R, Reiberger T, Uschner FE, Tacke F, Weiskirchen R, Trebicka J. Torres S, et al. Among authors: uschner fe. Int J Mol Sci. 2020 Mar 16;21(6):2027. doi: 10.3390/ijms21062027. Int J Mol Sci. 2020. PMID: 32188134 Free PMC article. Review.
Short-Term Western Diet Aggravates Non-Alcoholic Fatty Liver Disease (NAFLD) With Portal Hypertension in TGR(mREN2)27 Rats.
Cremonese C, Schierwagen R, Uschner FE, Torres S, Tyc O, Ortiz C, Schulz M, Queck A, Kristiansen G, Bader M, Sauerbruch T, Weiskirchen R, Walther T, Trebicka J, Klein S. Cremonese C, et al. Among authors: uschner fe. Int J Mol Sci. 2020 May 7;21(9):3308. doi: 10.3390/ijms21093308. Int J Mol Sci. 2020. PMID: 32392802 Free PMC article.
Combination of CCl4 with alcoholic and metabolic injuries mimics human liver fibrosis.
Brol MJ, Rösch F, Schierwagen R, Magdaleno F, Uschner FE, Manekeller S, Queck A, Schwarzkopf K, Odenthal M, Drebber U, Thiele M, Lingohr P, Plamper A, Kristiansen G, Lotersztajn S, Krag A, Klein S, Rheinwalt KP, Trebicka J. Brol MJ, et al. Among authors: uschner fe. Am J Physiol Gastrointest Liver Physiol. 2019 Aug 1;317(2):G182-G194. doi: 10.1152/ajpgi.00361.2018. Epub 2019 Jun 12. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 31188634 Free article.
TGR(mREN2)27 rats develop non-alcoholic fatty liver disease-associated portal hypertension responsive to modulations of Janus-kinase 2 and Mas receptor.
Klein S, Kleine CE, Pieper A, Granzow M, Gautsch S, Himmit M, Kahrmann K, Schierwagen R, Uschner FE, Magdaleno F, Naoum ME, Kristiansen G, Walther T, Bader M, Sauerbruch T, Trebicka J. Klein S, et al. Among authors: uschner fe. Sci Rep. 2019 Aug 12;9(1):11598. doi: 10.1038/s41598-019-48024-4. Sci Rep. 2019. PMID: 31406138 Free PMC article.
β-Arrestin2 is increased in liver fibrosis in humans and rodents.
Schierwagen R, Dietrich P, Klein S, Uschner FE, Ortiz C, Tyc O, Torres S, Hellerbrand C, Sauerbruch T, Trebicka J. Schierwagen R, et al. Among authors: uschner fe. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27082-27084. doi: 10.1073/pnas.2014337117. Proc Natl Acad Sci U S A. 2020. PMID: 33144522 Free PMC article. No abstract available.
Rationale for the use of statins in liver disease.
Schierwagen R, Uschner FE, Magdaleno F, Klein S, Trebicka J. Schierwagen R, et al. Among authors: uschner fe. Am J Physiol Gastrointest Liver Physiol. 2017 May 1;312(5):G407-G412. doi: 10.1152/ajpgi.00441.2016. Epub 2017 Mar 9. Am J Physiol Gastrointest Liver Physiol. 2017. PMID: 28280144 Free article. Review.
Combination of phosphodiesterase-5-inhibitors and beta blockers improves experimental portal hypertension and erectile dysfunction.
Uschner FE, Glückert K, Paternostro R, Gnad T, Schierwagen R, Mandorfer M, Magdaleno F, Ortiz C, Schwarzkopf K, Kamath PS, Alessandria C, Boesecke C, Pfeifer A, Reiberger T, Kreisel W, Sauerbruch T, Ferlitsch A, Trebicka J, Klein S. Uschner FE, et al. Liver Int. 2020 Sep;40(9):2228-2241. doi: 10.1111/liv.14586. Epub 2020 Jul 22. Liver Int. 2020. PMID: 32627946
The soluble guanylate cyclase stimulator riociguat reduces fibrogenesis and portal pressure in cirrhotic rats.
Schwabl P, Brusilovskaya K, Supper P, Bauer D, Königshofer P, Riedl F, Hayden H, Fuchs CD, Stift J, Oberhuber G, Aschauer S, Bonderman D, Gnad T, Pfeifer A, Uschner FE, Trebicka J, Rohr-Udilova N, Podesser BK, Peck-Radosavljevic M, Trauner M, Reiberger T. Schwabl P, et al. Among authors: uschner fe. Sci Rep. 2018 Jun 19;8(1):9372. doi: 10.1038/s41598-018-27656-y. Sci Rep. 2018. PMID: 29921982 Free PMC article.
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