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Page 1
New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming.
Colyn L, Alvarez-Sola G, Latasa MU, Uriarte I, Herranz JM, Arechederra M, Vlachogiannis G, Rae C, Pineda-Lucena A, Casadei-Gardini A, Pedica F, Aldrighetti L, López-López A, López-Gonzálvez A, Barbas C, Ciordia S, Van Liempd SM, Falcón-Pérez JM, Urman J, Sangro B, Vicent S, Iraburu MJ, Prosper F, Nelson LJ, Banales JM, Martinez-Chantar ML, Marin JJG, Braconi C, Trautwein C, Corrales FJ, Cubero FJ, Berasain C, Fernandez-Barrena MG, Avila MA. Colyn L, et al. Among authors: urman j. J Exp Clin Cancer Res. 2022 May 26;41(1):183. doi: 10.1186/s13046-022-02386-2. J Exp Clin Cancer Res. 2022. PMID: 35619118 Free PMC article.
Dual Targeting of G9a and DNA Methyltransferase-1 for the Treatment of Experimental Cholangiocarcinoma.
Colyn L, Bárcena-Varela M, Álvarez-Sola G, Latasa MU, Uriarte I, Santamaría E, Herranz JM, Santos-Laso A, Arechederra M, Ruiz de Gauna M, Aspichueta P, Canale M, Casadei-Gardini A, Francesconi M, Carotti S, Morini S, Nelson LJ, Iraburu MJ, Chen C, Sangro B, Marin JJG, Martinez-Chantar ML, Banales JM, Arnes-Benito R, Huch M, Patino JM, Dar AA, Nosrati M, Oyarzábal J, Prósper F, Urman J, Cubero FJ, Trautwein C, Berasain C, Fernandez-Barrena MG, Avila MA. Colyn L, et al. Among authors: urman j. Hepatology. 2021 Jun;73(6):2380-2396. doi: 10.1002/hep.31642. Hepatology. 2021. PMID: 33222246
Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach.
Urman JM, Herranz JM, Uriarte I, Rullán M, Oyón D, González B, Fernandez-Urién I, Carrascosa J, Bolado F, Zabalza L, Arechederra M, Alvarez-Sola G, Colyn L, Latasa MU, Puchades-Carrasco L, Pineda-Lucena A, Iraburu MJ, Iruarrizaga-Lejarreta M, Alonso C, Sangro B, Purroy A, Gil I, Carmona L, Cubero FJ, Martínez-Chantar ML, Banales JM, Romero MR, Macias RIR, Monte MJ, Marín JJG, Vila JJ, Corrales FJ, Berasain C, Fernández-Barrena MG, Avila MA. Urman JM, et al. Cancers (Basel). 2020 Jun 21;12(6):1644. doi: 10.3390/cancers12061644. Cancers (Basel). 2020. PMID: 32575903 Free PMC article.
Digging deeper into bile proteome.
Ciordia S, Alvarez-Sola G, Rullán M, Urman JM, Ávila MA, Corrales FJ. Ciordia S, et al. Among authors: urman jm. J Proteomics. 2021 Jan 6;230:103984. doi: 10.1016/j.jprot.2020.103984. Epub 2020 Sep 12. J Proteomics. 2021. PMID: 32932008
Epigenetics in Liver Fibrosis: Could HDACs be a Therapeutic Target?
Claveria-Cabello A, Colyn L, Arechederra M, Urman JM, Berasain C, Avila MA, Fernandez-Barrena MG. Claveria-Cabello A, et al. Among authors: urman jm. Cells. 2020 Oct 19;9(10):2321. doi: 10.3390/cells9102321. Cells. 2020. PMID: 33086678 Free PMC article. Review.
Dual Pharmacological Targeting of HDACs and PDE5 Inhibits Liver Disease Progression in a Mouse Model of Biliary Inflammation and Fibrosis.
Claveria-Cabello A, Colyn L, Uriarte I, Latasa MU, Arechederra M, Herranz JM, Alvarez L, Urman JM, Martinez-Chantar ML, Banales JM, Sangro B, Rombouts K, Oyarzabal J, Marin JJG, Berasain C, Avila MA, Fernandez-Barrena MG. Claveria-Cabello A, et al. Among authors: urman jm. Cancers (Basel). 2020 Dec 13;12(12):3748. doi: 10.3390/cancers12123748. Cancers (Basel). 2020. PMID: 33322158 Free PMC article.
Bile Processing Protocol for Improved Proteomic Analysis.
Ciordia S, Alvarez-Sola G, Rullán M, Urman JM, Ávila MA, Corrales FJ. Ciordia S, et al. Among authors: urman jm. Methods Mol Biol. 2022;2420:1-10. doi: 10.1007/978-1-0716-1936-0_1. Methods Mol Biol. 2022. PMID: 34905161
HOXD8 hypermethylation as a fully sensitive and specific biomarker for biliary tract cancer detectable in tissue and bile samples.
Loi E, Zavattari C, Tommasi A, Moi L, Canale M, Po A, Sabato C, Vega-Benedetti AF, Ziranu P, Puzzoni M, Lai E, Faloppi L, Rullán M, Carrascosa J, Amat I, Urman JM, Arechederra M, Berasain C, Ferretti E, Casadei-Gardini A, Avila MA, Alonso S, Scartozzi M, Zavattari P. Loi E, et al. Among authors: urman jm. Br J Cancer. 2022 Jun;126(12):1783-1794. doi: 10.1038/s41416-022-01738-1. Epub 2022 Feb 17. Br J Cancer. 2022. PMID: 35177798 Free PMC article.
Next-generation sequencing of bile cell-free DNA for the early detection of patients with malignant biliary strictures.
Arechederra M, Rullán M, Amat I, Oyon D, Zabalza L, Elizalde M, Latasa MU, Mercado MR, Ruiz-Clavijo D, Saldaña C, Fernández-Urién I, Carrascosa J, Jusué V, Guerrero-Setas D, Zazpe C, González-Borja I, Sangro B, Herranz JM, Purroy A, Gil I, Nelson LJ, Vila JJ, Krawczyk M, Zieniewicz K, Patkowski W, Milkiewicz P, Cubero FJ, Alkorta-Aranburu G, G Fernandez-Barrena M, Urman JM, Berasain C, Avila MA. Arechederra M, et al. Among authors: urman jm. Gut. 2022 Jun;71(6):1141-1151. doi: 10.1136/gutjnl-2021-325178. Epub 2021 Jul 20. Gut. 2022. PMID: 34285068 Free PMC article.
56 results