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MEK inhibitors block growth of lung tumours with mutations in ataxia-telangiectasia mutated.
Smida M, Fece de la Cruz F, Kerzendorfer C, Uras IZ, Mair B, Mazouzi A, Suchankova T, Konopka T, Katz AM, Paz K, Nagy-Bojarszky K, Muellner MK, Bago-Horvath Z, Haura EB, Loizou JI, Nijman SM. Smida M, et al. Among authors: uras iz. Nat Commun. 2016 Dec 6;7:13701. doi: 10.1038/ncomms13701. Nat Commun. 2016. PMID: 27922010 Free PMC article.
CDK6 Antagonizes p53-Induced Responses during Tumorigenesis.
Bellutti F, Tigan AS, Nebenfuehr S, Dolezal M, Zojer M, Grausenburger R, Hartenberger S, Kollmann S, Doma E, Prchal-Murphy M, Uras IZ, Höllein A, Neuberg DS, Ebert BL, Ringler A, Mueller AC, Loizou JI, Hinds PW, Vogl C, Heller G, Kubicek S, Zuber J, Malumbres M, Farlik M, Villunger A, Kollmann K, Sexl V. Bellutti F, et al. Among authors: uras iz. Cancer Discov. 2018 Jul;8(7):884-897. doi: 10.1158/2159-8290.CD-17-0912. Epub 2018 Jun 13. Cancer Discov. 2018. PMID: 29899063 Free PMC article.
A kinase-independent role for CDK8 in BCR-ABL1+ leukemia.
Menzl I, Zhang T, Berger-Becvar A, Grausenburger R, Heller G, Prchal-Murphy M, Edlinger L, Knab VM, Uras IZ, Grundschober E, Bauer K, Roth M, Skucha A, Liu Y, Hatcher JM, Liang Y, Kwiatkowski NP, Fux D, Hoelbl-Kovacic A, Kubicek S, Melo JV, Valent P, Weichhart T, Grebien F, Zuber J, Gray NS, Sexl V. Menzl I, et al. Among authors: uras iz. Nat Commun. 2019 Oct 18;10(1):4741. doi: 10.1038/s41467-019-12656-x. Nat Commun. 2019. PMID: 31628323 Free PMC article.
18 results