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(+)-trans-Cannabidiol-2-hydroxy pentyl is a dual CB1R antagonist/CB2R agonist that prevents diabetic nephropathy in mice.
González-Mariscal I, Carmona-Hidalgo B, Winkler M, Unciti-Broceta JD, Escamilla A, Gómez-Cañas M, Fernández-Ruiz J, Fiebich BL, Romero-Zerbo SY, Bermúdez-Silva FJ, Collado JA, Muñoz E. González-Mariscal I, et al. Among authors: unciti broceta jd. Pharmacol Res. 2021 Jul;169:105492. doi: 10.1016/j.phrs.2021.105492. Epub 2021 May 19. Pharmacol Res. 2021. PMID: 34019978
Isomeric O-methyl cannabidiolquinones with dual BACH1/NRF2 activity.
Casares L, Unciti-Broceta JD, Prados ME, Caprioglio D, Mattoteia D, Higgins M, Apendino G, Dinkova-Kostova AT, Muñoz E, de la Vega L. Casares L, et al. Among authors: unciti broceta jd. Redox Biol. 2020 Oct;37:101689. doi: 10.1016/j.redox.2020.101689. Epub 2020 Aug 22. Redox Biol. 2020. PMID: 32863231 Free PMC article.
Betulinic Acid Hydroxamate is Neuroprotective and Induces Protein Phosphatase 2A-Dependent HIF-1α Stabilization and Post-transcriptional Dephosphorylation of Prolyl Hydrolase 2.
Prados ME, Correa-Sáez A, Unciti-Broceta JD, Garrido-Rodríguez M, Jimenez-Jimenez C, Mazzone M, Minassi A, Appendino G, Calzado MA, Muñoz E. Prados ME, et al. Among authors: unciti broceta jd. Neurotherapeutics. 2021 Jul;18(3):1849-1861. doi: 10.1007/s13311-021-01089-4. Epub 2021 Aug 2. Neurotherapeutics. 2021. PMID: 34339019 Free PMC article.
The dimerization of Δ 9-tetrahydrocannabinolic acid A (THCA-A).
Cuadari A, Pollastro F, Unciti-Broceta JD, Caprioglio D, Minassi A, Lopatriello A, Muñoz E, Taglialatela-Scafati O, Appendino G. Cuadari A, et al. Among authors: unciti broceta jd. Acta Pharm Sin B. 2019 Sep;9(5):1078-1083. doi: 10.1016/j.apsb.2019.06.007. Epub 2019 Jun 24. Acta Pharm Sin B. 2019. PMID: 31649855 Free PMC article.
Novel therapy based on camelid nanobodies.
Unciti-Broceta JD, Del Castillo T, Soriano M, Magez S, Garcia-Salcedo JA. Unciti-Broceta JD, et al. Ther Deliv. 2013 Oct;4(10):1321-36. doi: 10.4155/tde.13.87. Ther Deliv. 2013. PMID: 24116915 Review.
20 results