Ulrichts H - Search Results

1

Caplacizumab for Acquired Thrombotic Thrombocytopenic Purpura.

Peyvandi F, Scully M, Kremer Hovinga JA, Cataland S, Knöbl P, Wu H, Artoni A, Westwood JP, Mansouri Taleghani M, Jilma B, Callewaert F, Ulrichts H, Duby C, Tersago D; TITAN Investigators. Peyvandi F, et al. Among authors: ulrichts h. N Engl J Med. 2016 Feb 11;374(6):511-22. doi: 10.1056/NEJMoa1505533. N Engl J Med. 2016. PMID: 26863353 Free article. Clinical Trial.

2

Evaluation of efficacy and safety of the anti-VWF Nanobody ALX-0681 in a preclinical baboon model of acquired thrombotic thrombocytopenic purpura.

Callewaert F, Roodt J, Ulrichts H, Stohr T, van Rensburg WJ, Lamprecht S, Rossenu S, Priem S, Willems W, Holz JB. Callewaert F, et al. Among authors: ulrichts h. Blood. 2012 Oct 25;120(17):3603-10. doi: 10.1182/blood-2012-04-420943. Epub 2012 Sep 4. Blood. 2012. PMID: 22948047 Free article.

3

Development of monoclonal antibodies that inhibit platelet adhesion or aggregation as potential anti-thrombotic drugs.

De Meyer SF, Vanhoorelbeke K, Ulrichts H, Staelens S, Feys HB, Salles I, Fontayne A, Deckmyn H. De Meyer SF, et al. Among authors: ulrichts h. Cardiovasc Hematol Disord Drug Targets. 2006 Sep;6(3):191-207. doi: 10.2174/187152906778249536. Cardiovasc Hematol Disord Drug Targets. 2006. PMID: 17017902 Review.

4

Antithrombotic drug candidate ALX-0081 shows superior preclinical efficacy and safety compared with currently marketed antiplatelet drugs.

Ulrichts H, Silence K, Schoolmeester A, de Jaegere P, Rossenu S, Roodt J, Priem S, Lauwereys M, Casteels P, Van Bockstaele F, Verschueren K, Stanssens P, Baumeister J, Holz JB. Ulrichts H, et al. Blood. 2011 Jul 21;118(3):757-65. doi: 10.1182/blood-2010-11-317859. Epub 2011 May 16. Blood. 2011. PMID: 21576702 Free article.

5

Reperfusion of cerebral artery thrombosis by the GPIb-VWF blockade with the Nanobody ALX-0081 reduces brain infarct size in guinea pigs.

Momi S, Tantucci M, Van Roy M, Ulrichts H, Ricci G, Gresele P. Momi S, et al. Among authors: ulrichts h. Blood. 2013 Jun 20;121(25):5088-97. doi: 10.1182/blood-2012-11-464545. Epub 2013 Apr 15. Blood. 2013. PMID: 23589671 Free article.

6

The in vitro effect of the new antithrombotic drug candidate ALX-0081 on blood samples of patients undergoing percutaneous coronary intervention.

van Loon JE, de Jaegere PP, Ulrichts H, van Vliet HH, de Maat MP, de Groot PG, Simoons ML, Leebeek FW. van Loon JE, et al. Among authors: ulrichts h. Thromb Haemost. 2011 Jul;106(1):165-71. doi: 10.1160/TH10-12-0804. Epub 2011 Jun 9. Thromb Haemost. 2011. PMID: 21655675

7

A monoclonal antibody directed against human von Willebrand factor induces type 2B-like alterations.

Ulrichts H, Harsfalvi J, Bene L, Matko J, Vermylen J, Ajzenberg N, Baruch D, Deckmyn H, Tornai I. Ulrichts H, et al. J Thromb Haemost. 2004 Sep;2(9):1622-8. doi: 10.1111/j.1538-7836.2004.00865.x. J Thromb Haemost. 2004. PMID: 15333040 Free article.

8

The preclinical pharmacology of the high affinity anti-IL-6R Nanobody® ALX-0061 supports its clinical development in rheumatoid arthritis.

Van Roy M, Ververken C, Beirnaert E, Hoefman S, Kolkman J, Vierboom M, Breedveld E, 't Hart B, Poelmans S, Bontinck L, Hemeryck A, Jacobs S, Baumeister J, Ulrichts H. Van Roy M, et al. Among authors: ulrichts h. Arthritis Res Ther. 2015 May 20;17(1):135. doi: 10.1186/s13075-015-0651-0. Arthritis Res Ther. 2015. PMID: 25994180 Free PMC article.

9

Relation of endothelial function to residual platelet reactivity after clopidogrel in patients with stable angina pectoris undergoing percutaneous coronary intervention.

Muller O, Hamilos M, Bartunek J, Ulrichts H, Mangiacapra F, Holz JB, Ntalianis A, Trana C, Dierickx K, Vercruysse K, De Bruyne B, Wijns W, Barbato E. Muller O, et al. Among authors: ulrichts h. Am J Cardiol. 2010 Feb 1;105(3):333-8. doi: 10.1016/j.amjcard.2009.09.033. Epub 2009 Dec 22. Am J Cardiol. 2010. PMID: 20102944

10

Platelet microparticle formation and thrombin generation under high shear are effectively suppressed by a monoclonal antibody against GPIba.

Pontiggia L, Steiner B, Ulrichts H, Deckmyn H, Forestier M, Beer JH. Pontiggia L, et al. Among authors: ulrichts h. Thromb Haemost. 2006 Dec;96(6):774-80. Thromb Haemost. 2006. PMID: 17139372

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