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Riluzole-Rasagiline Hybrids: Toward the Development of Multi-Target-Directed Ligands for Amyotrophic Lateral Sclerosis.
Albertini C, Salerno A, Atzeni S, Uliassi E, Massenzio F, Maruca A, Rocca R, Mecava M, Silva FSG, Mena D, Valente P, Duarte AI, Chavarria D, Bissaro M, Moro S, Federico S, Spalluto G, Soukup O, Borges F, Alcaro S, Monti B, Oliveira PJ, Menéndez JC, Bolognesi ML. Albertini C, et al. Among authors: uliassi e. ACS Chem Neurosci. 2022 Aug 3;13(15):2252-2260. doi: 10.1021/acschemneuro.2c00261. Epub 2022 Jul 22. ACS Chem Neurosci. 2022. PMID: 35868251 Free PMC article.
Toward the development of dual-targeted glyceraldehyde-3-phosphate dehydrogenase/trypanothione reductase inhibitors against Trypanosoma brucei and Trypanosoma cruzi.
Belluti F, Uliassi E, Veronesi G, Bergamini C, Kaiser M, Brun R, Viola A, Fato R, Michels PA, Krauth-Siegel RL, Cavalli A, Bolognesi ML. Belluti F, et al. Among authors: uliassi e. ChemMedChem. 2014 Feb;9(2):371-82. doi: 10.1002/cmdc.201300399. Epub 2014 Jan 8. ChemMedChem. 2014. PMID: 24403089
Multitarget drug design strategy: quinone-tacrine hybrids designed to block amyloid-β aggregation and to exert anticholinesterase and antioxidant effects.
Nepovimova E, Uliassi E, Korabecny J, Peña-Altamira LE, Samez S, Pesaresi A, Garcia GE, Bartolini M, Andrisano V, Bergamini C, Fato R, Lamba D, Roberti M, Kuca K, Monti B, Bolognesi ML. Nepovimova E, et al. Among authors: uliassi e. J Med Chem. 2014 Oct 23;57(20):8576-89. doi: 10.1021/jm5010804. Epub 2014 Oct 10. J Med Chem. 2014. PMID: 25259726
Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease.
Jeřábek J, Uliassi E, Guidotti L, Korábečný J, Soukup O, Sepsova V, Hrabinova M, Kuča K, Bartolini M, Peña-Altamira LE, Petralla S, Monti B, Roberti M, Bolognesi ML. Jeřábek J, et al. Among authors: uliassi e. Eur J Med Chem. 2017 Feb 15;127:250-262. doi: 10.1016/j.ejmech.2016.12.048. Epub 2016 Dec 26. Eur J Med Chem. 2017. PMID: 28064079
Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule.
Bruno S, Uliassi E, Zaffagnini M, Prati F, Bergamini C, Amorati R, Paredi G, Margiotta M, Conti P, Costi MP, Kaiser M, Cavalli A, Fato R, Bolognesi ML. Bruno S, et al. Among authors: uliassi e. Chem Biol Drug Des. 2017 Aug;90(2):225-235. doi: 10.1111/cbdd.12941. Epub 2017 Mar 6. Chem Biol Drug Des. 2017. PMID: 28079302 Free article.
Development of a Focused Library of Triazole-Linked Privileged-Structure-Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections.
Uliassi E, Piazzi L, Belluti F, Mazzanti A, Kaiser M, Brun R, Moraes CB, Freitas-Junior LH, Gul S, Kuzikov M, Ellinger B, Borsari C, Costi MP, Bolognesi ML. Uliassi E, et al. ChemMedChem. 2018 Apr 6;13(7):678-683. doi: 10.1002/cmdc.201700786. Epub 2018 Feb 16. ChemMedChem. 2018. PMID: 29451361
33 results