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NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component.
Shi H, Wang Y, Li X, Zhan X, Tang M, Fina M, Su L, Pratt D, Bu CH, Hildebrand S, Lyon S, Scott L, Quan J, Sun Q, Russell J, Arnett S, Jurek P, Chen D, Kravchenko VV, Mathison JC, Moresco EM, Monson NL, Ulevitch RJ, Beutler B. Shi H, et al. Among authors: ulevitch rj. Nat Immunol. 2016 Mar;17(3):250-8. doi: 10.1038/ni.3333. Epub 2015 Dec 7. Nat Immunol. 2016. PMID: 26642356 Free PMC article.
MDP-induced interleukin-1beta processing requires Nod2 and CIAS1/NALP3.
Pan Q, Mathison J, Fearns C, Kravchenko VV, Da Silva Correia J, Hoffman HM, Kobayashi KS, Bertin J, Grant EP, Coyle AJ, Sutterwala FS, Ogura Y, Flavell RA, Ulevitch RJ. Pan Q, et al. Among authors: ulevitch rj. J Leukoc Biol. 2007 Jul;82(1):177-83. doi: 10.1189/jlb.1006627. Epub 2007 Apr 2. J Leukoc Biol. 2007. PMID: 17403772
Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism.
Werts C, Tapping RI, Mathison JC, Chuang TH, Kravchenko V, Saint Girons I, Haake DA, Godowski PJ, Hayashi F, Ozinsky A, Underhill DM, Kirschning CJ, Wagner H, Aderem A, Tobias PS, Ulevitch RJ. Werts C, et al. Among authors: ulevitch rj. Nat Immunol. 2001 Apr;2(4):346-52. doi: 10.1038/86354. Nat Immunol. 2001. PMID: 11276206
209 results