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Page 1
Dimeric Glycoprotein VI Binds to Collagen but Not to Fibrin.
Ebrahim M, Jamasbi J, Adler K, Megens RTA, M'Bengue Y, Blanchet X, Uhland K, Ungerer M, Brandl R, Weber C, Elia N, Lorenz R, Münch G, Siess W. Ebrahim M, et al. Among authors: uhland k. Thromb Haemost. 2018 Feb;118(2):351-361. doi: 10.1160/TH17-04-0302. Epub 2018 Jan 29. Thromb Haemost. 2018. PMID: 29378359
Cross-Linking GPVI-Fc by Anti-Fc Antibodies Potentiates Its Inhibition of Atherosclerotic Plaque- and Collagen-Induced Platelet Activation.
Jamasbi J, Megens RT, Bianchini M, Uhland K, Münch G, Ungerer M, Sherman S, Faussner A, Brandl R, John C, Buchner J, Weber C, Lorenz R, Elia N, Siess W. Jamasbi J, et al. Among authors: uhland k. JACC Basic Transl Sci. 2016 Apr 25;1(3):131-142.. doi: 10.1016/j.jacbts.2016.03.008. eCollection 2016 Apr. JACC Basic Transl Sci. 2016. PMID: 27766315 Free PMC article. Review.
Novel antiplatelet drug revacept (Dimeric Glycoprotein VI-Fc) specifically and efficiently inhibited collagen-induced platelet aggregation without affecting general hemostasis in humans.
Ungerer M, Rosport K, Bültmann A, Piechatzek R, Uhland K, Schlieper P, Gawaz M, Münch G. Ungerer M, et al. Among authors: uhland k. Circulation. 2011 May 3;123(17):1891-9. doi: 10.1161/CIRCULATIONAHA.110.980623. Epub 2011 Apr 18. Circulation. 2011. PMID: 21502572 Clinical Trial.
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