Ueda S - Search Results

1

Therapeutic potential of the chemokine receptor CXCR4 antagonists as multifunctional agents.

Tsutsumi H, Tanaka T, Ohashi N, Masuno H, Tamamura H, Hiramatsu K, Araki T, Ueda S, Oishi S, Fujii N. Tsutsumi H, et al. Among authors: ueda s. Biopolymers. 2007;88(2):279-89. doi: 10.1002/bip.20653. Biopolymers. 2007. PMID: 17167792 Review.

2

Structure-activity relationship studies on CXCR4 antagonists having cyclic pentapeptide scaffolds.

Tamamura H, Esaka A, Ogawa T, Araki T, Ueda S, Wang Z, Trent JO, Tsutsumi H, Masuno H, Nakashima H, Yamamoto N, Peiper SC, Otaka A, Fujii N. Tamamura H, et al. Among authors: ueda s. Org Biomol Chem. 2005 Dec 21;3(24):4392-4. doi: 10.1039/b513145f. Epub 2005 Nov 15. Org Biomol Chem. 2005. PMID: 16327900

3

Development of chemokine receptor CXCR4 antagonists using bio-mimetic strategy.

Tamamura H, Tanaka T, Tsutsumi H, Ohashi N, Hiramatsu K, Araki T, Ojida A, Hamachi I, Wang Z, Peiper SC, Trent JO, Ueda S, Oishi S, Fujii N. Tamamura H, et al. Among authors: ueda s. Adv Exp Med Biol. 2009;611:145-6. doi: 10.1007/978-0-387-73657-0_65. Adv Exp Med Biol. 2009. PMID: 19400132 No abstract available.

4

Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries.

Fujii N, Oishi S, Hiramatsu K, Araki T, Ueda S, Tamamura H, Otaka A, Kusano S, Terakubo S, Nakashima H, Broach JA, Trent JO, Wang ZX, Peiper SC. Fujii N, et al. Among authors: ueda s. Angew Chem Int Ed Engl. 2003 Jul 21;42(28):3251-3. doi: 10.1002/anie.200351024. Angew Chem Int Ed Engl. 2003. PMID: 12876735 No abstract available.

5

Enhancement of the T140-based pharmacophores leads to the development of more potent and bio-stable CXCR4 antagonists.

Tamamura H, Hiramatsu K, Mizumoto M, Ueda S, Kusano S, Terakubo S, Akamatsu M, Yamamoto N, Trent JO, Wang Z, Peiper SC, Nakashima H, Otaka A, Fujii N. Tamamura H, et al. Among authors: ueda s. Org Biomol Chem. 2003 Nov 7;1(21):3663-9. doi: 10.1039/b306613b. Org Biomol Chem. 2003. PMID: 14649897

6

Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131.

Tamamura H, Hiramatsu K, Ueda S, Wang Z, Kusano S, Terakubo S, Trent JO, Peiper SC, Yamamoto N, Nakashima H, Otaka A, Fujii N. Tamamura H, et al. Among authors: ueda s. J Med Chem. 2005 Jan 27;48(2):380-91. doi: 10.1021/jm049429h. J Med Chem. 2005. PMID: 15658852

7

Identification of novel low molecular weight CXCR4 antagonists by structural tuning of cyclic tetrapeptide scaffolds.

Tamamura H, Araki T, Ueda S, Wang Z, Oishi S, Esaka A, Trent JO, Nakashima H, Yamamoto N, Peiper SC, Otaka A, Fujii N. Tamamura H, et al. Among authors: ueda s. J Med Chem. 2005 May 5;48(9):3280-9. doi: 10.1021/jm050009h. J Med Chem. 2005. PMID: 15857134

8

Structure-activity relationships of cyclic peptide-based chemokine receptor CXCR4 antagonists: disclosing the importance of side-chain and backbone functionalities.

Ueda S, Oishi S, Wang ZX, Araki T, Tamamura H, Cluzeau J, Ohno H, Kusano S, Nakashima H, Trent JO, Peiper SC, Fujii N. Ueda S, et al. J Med Chem. 2007 Jan 25;50(2):192-8. doi: 10.1021/jm0607350. J Med Chem. 2007. PMID: 17228861

9

Synthesis and application of fluorescein- and biotin-labeled molecular probes for the chemokine receptor CXCR4.

Oishi S, Masuda R, Evans B, Ueda S, Goto Y, Ohno H, Hirasawa A, Tsujimoto G, Wang Z, Peiper SC, Naito T, Kodama E, Matsuoka M, Fujii N. Oishi S, et al. Among authors: ueda s. Chembiochem. 2008 May 5;9(7):1154-8. doi: 10.1002/cbic.200700761. Chembiochem. 2008. PMID: 18412193

10

Identification of novel non-peptide CXCR4 antagonists by ligand-based design approach.

Ueda S, Kato M, Inuki S, Ohno H, Evans B, Wang ZX, Peiper SC, Izumi K, Kodama E, Matsuoka M, Nagasawa H, Oishi S, Fujii N. Ueda S, et al. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4124-9. doi: 10.1016/j.bmcl.2008.05.092. Epub 2008 May 29. Bioorg Med Chem Lett. 2008. PMID: 18539453

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