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Distinct transcription factor networks control neutrophil-driven inflammation.
Khoyratty TE, Ai Z, Ballesteros I, Eames HL, Mathie S, Martín-Salamanca S, Wang L, Hemmings A, Willemsen N, von Werz V, Zehrer A, Walzog B, van Grinsven E, Hidalgo A, Udalova IA. Khoyratty TE, et al. Among authors: udalova ia. Nat Immunol. 2021 Sep;22(9):1093-1106. doi: 10.1038/s41590-021-00968-4. Epub 2021 Jul 19. Nat Immunol. 2021. PMID: 34282331 Free PMC article.
IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses.
Krausgruber T, Blazek K, Smallie T, Alzabin S, Lockstone H, Sahgal N, Hussell T, Feldmann M, Udalova IA. Krausgruber T, et al. Among authors: udalova ia. Nat Immunol. 2011 Mar;12(3):231-8. doi: 10.1038/ni.1990. Epub 2011 Jan 16. Nat Immunol. 2011. PMID: 21240265
KAP1/TRIM28: an inhibitor of IRF5 function in inflammatory macrophages.
Eames HL, Saliba DG, Krausgruber T, Lanfrancotti A, Ryzhakov G, Udalova IA. Eames HL, et al. Among authors: udalova ia. Immunobiology. 2012 Dec;217(12):1315-24. doi: 10.1016/j.imbio.2012.07.026. Epub 2012 Aug 11. Immunobiology. 2012. PMID: 22995936 Free article.
IRF5:RelA interaction targets inflammatory genes in macrophages.
Saliba DG, Heger A, Eames HL, Oikonomopoulos S, Teixeira A, Blazek K, Androulidaki A, Wong D, Goh FG, Weiss M, Byrne A, Pasparakis M, Ragoussis J, Udalova IA. Saliba DG, et al. Among authors: udalova ia. Cell Rep. 2014 Sep 11;8(5):1308-17. doi: 10.1016/j.celrep.2014.07.034. Epub 2014 Aug 21. Cell Rep. 2014. PMID: 25159141 Free PMC article.
Activation and function of interferon regulatory factor 5.
Ryzhakov G, Eames HL, Udalova IA. Ryzhakov G, et al. Among authors: udalova ia. J Interferon Cytokine Res. 2015 Feb;35(2):71-8. doi: 10.1089/jir.2014.0023. Epub 2014 Sep 26. J Interferon Cytokine Res. 2015. PMID: 25259415 Review.
Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity.
Dalmas E, Toubal A, Alzaid F, Blazek K, Eames HL, Lebozec K, Pini M, Hainault I, Montastier E, Denis RG, Ancel P, Lacombe A, Ling Y, Allatif O, Cruciani-Guglielmacci C, André S, Viguerie N, Poitou C, Stich V, Torcivia A, Foufelle F, Luquet S, Aron-Wisnewsky J, Langin D, Clément K, Udalova IA, Venteclef N. Dalmas E, et al. Among authors: udalova ia. Nat Med. 2015 Jun;21(6):610-8. doi: 10.1038/nm.3829. Epub 2015 May 4. Nat Med. 2015. PMID: 25939064
A critical role for IRF5 in regulating allergic airway inflammation.
Byrne AJ, Weiss M, Mathie SA, Walker SA, Eames HL, Saliba D, Lloyd CM, Udalova IA. Byrne AJ, et al. Among authors: udalova ia. Mucosal Immunol. 2017 May;10(3):716-726. doi: 10.1038/mi.2016.92. Epub 2016 Oct 19. Mucosal Immunol. 2017. PMID: 27759022 Free PMC article.
Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis.
Seneviratne AN, Edsfeldt A, Cole JE, Kassiteridi C, Swart M, Park I, Green P, Khoyratty T, Saliba D, Goddard ME, Sansom SN, Goncalves I, Krams R, Udalova IA, Monaco C. Seneviratne AN, et al. Among authors: udalova ia. Circulation. 2017 Sep 19;136(12):1140-1154. doi: 10.1161/CIRCULATIONAHA.117.027844. Epub 2017 Jul 11. Circulation. 2017. PMID: 28698173 Free PMC article.
108 results