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Incomplete recovery of the CD4+/CD8+ ratio is associated with the late introduction of antiretroviral therapy among people living with HIV infection.
Prates GDS, Monteiro MA, Oliveira ÉC, Nascimento NAL, Veiga APR, Ferreira MD, Polis TJB, Caetano GP, Soares BRP, Magri MMC, Pereira LO, Fonseca LAM, Alves WS, Duarte AJDS, Casseb JSDR. Prates GDS, et al. Rev Inst Med Trop Sao Paulo. 2024 Feb 5;66:e7. doi: 10.1590/S1678-9946202466007. eCollection 2024. Rev Inst Med Trop Sao Paulo. 2024. PMID: 38324873 Free PMC article.
Rate of response to initial antiretroviral therapy according to level of pre-existing HIV-1 drug resistance detected by next-generation sequencing in the strategic timing of antiretroviral treatment (START) study.
Cozzi-Lepri A, Dunn D, Tostevin A, Marvig RL, Bennedbaek M, Sharma S, Kozal MJ, Gompels M, Pinto AN, Lundgren J, Baxter JD; INSIGHT START Study Group. Cozzi-Lepri A, et al. HIV Med. 2024 Feb;25(2):212-222. doi: 10.1111/hiv.13556. Epub 2023 Sep 29. HIV Med. 2024. PMID: 37775947
Faster lung function decline in people living with HIV despite adequate treatment: a longitudinal matched cohort study.
Thudium RF, Ronit A, Afzal S, Çolak Y, Forman JL, Mendo F, Chen F, Estrada V, Kumarasamy N, Nordestgaard BG, Lundgren J, Vestbo J, Kunisaki KM, Nielsen SD; COCOMO, INSIGHT START Pulmonary Substudy and CGPS Study Groups. Thudium RF, et al. Thorax. 2023 Jun;78(6):535-542. doi: 10.1136/thorax-2022-218910. Epub 2023 Jan 13. Thorax. 2023. PMID: 36639241
Deep-sequencing of viral genomes from a large and diverse cohort of treatment-naive HIV-infected persons shows associations between intrahost genetic diversity and viral load.
Gabrielaite M, Bennedbæk M, Rasmussen MS, Kan V, Furrer H, Flisiak R, Losso M, Lundgren JD; INSIGHT START Study Group; Marvig RL. Gabrielaite M, et al. PLoS Comput Biol. 2023 Jan 3;19(1):e1010756. doi: 10.1371/journal.pcbi.1010756. eCollection 2023 Jan. PLoS Comput Biol. 2023. PMID: 36595537 Free PMC article.
Human Immunotypes Impose Selection on Viral Genotypes Through Viral Epitope Specificity.
Gabrielaite M, Bennedbæk M, Zucco AG, Ekenberg C, Murray DD, Kan VL, Touloumi G, Vandekerckhove L, Turner D, Neaton J, Lane HC, Safo S, Arenas-Pinto A, Polizzotto MN, Günthard HF, Lundgren JD, Marvig RL. Gabrielaite M, et al. J Infect Dis. 2021 Dec 15;224(12):2053-2063. doi: 10.1093/infdis/jiab253. J Infect Dis. 2021. PMID: 33974707 Free PMC article.
DNA methylation is associated with airflow obstruction in patients living with HIV.
Hernandez Cordero AI, Yang CX, Obeidat M, Yang J, MacIsaac J, McEwen L, Lin D, Kobor M, Novak R, Hudson F, Klinker H, Dharan N, Man SP, Sin DD, Kunisaki K, Leung J; INSIGHT START Pulmonary and Genomic Substudy Groups. Hernandez Cordero AI, et al. Thorax. 2021 May;76(5):448-455. doi: 10.1136/thoraxjnl-2020-215866. Epub 2020 Dec 18. Thorax. 2021. PMID: 33443234 Free PMC article. Clinical Trial.
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