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Page 1
Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial.
Lancet Respir Med. 2015 Sep;3(9):684-691. doi: 10.1016/S2213-2600(15)00245-3. Epub 2015 Jul 3.
Lancet Respir Med. 2015.
PMID: 26149841
Free PMC article.
Clinical Trial.
A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis.
Alton EWFW, Armstrong DK, Ashby D, Bayfield KJ, Bilton D, Bloomfield EV, Boyd AC, Brand J, Buchan R, Calcedo R, Carvelli P, Chan M, Cheng SH, Collie DS, Cunningham S, Davidson HE, Davies G, Davies JC, Davies LA, Dewar MH, Doherty A, Donovan J, Dwyer NS, Elgmati HI, Featherstone RF, Gavino J, Gea-Sorli S, Geddes DM, Gibson JSR, Gill DR, Greening AP, Griesenbach U, Hansell DM, Harman K, Higgins TE, Hodges SL, Hyde SC, Hyndman L, Innes JA, Jacob J, Jones N, Keogh BF, Limberis MP, Lloyd-Evans P, Maclean AW, Manvell MC, McCormick D, McGovern M, McLachlan G, Meng C, Montero MA, Milligan H, Moyce LJ, Murray GD, Nicholson AG, Osadolor T, Parra-Leiton J, Porteous DJ, Pringle IA, Punch EK, Pytel KM, Quittner AL, Rivellini G, Saunders CJ, Scheule RK, Sheard S, Simmonds NJ, Smith K, Smith SN, Soussi N, Soussi S, Spearing EJ, Stevenson BJ, Sumner-Jones SG, Turkkila M, Ureta RP, Waller MD, Wasowicz MY, Wilson JM, Wolstenholme-Hogg P; on behalf of the UK Cystic Fibrosis Gene Therapy Consortium.
Alton EWFW, et al.
Southampton (UK): NIHR Journals Library; 2016 Jul.
Southampton (UK): NIHR Journals Library; 2016 Jul.
PMID: 27441329
Free Books & Documents.
Review.
Item in Clipboard
Pre-clinical and clinical endpoint assays for cystic fibrosis gene therapy.
Griesenbach U, Boyd AC; UK Cystic Fibrosis Gene Therapy Consortium.
Griesenbach U, et al.
J Cyst Fibros. 2005 May;4(2):89-100. doi: 10.1016/j.jcf.2005.02.002.
J Cyst Fibros. 2005.
PMID: 15914096
Free article.
Review.
Item in Clipboard
Gene transfer to the lung: lessons learned from more than 2 decades of CF gene therapy.
Griesenbach U, Alton EW; UK Cystic Fibrosis Gene Therapy Consortium.
Griesenbach U, et al.
Adv Drug Deliv Rev. 2009 Feb 27;61(2):128-39. doi: 10.1016/j.addr.2008.09.010. Epub 2008 Dec 24.
Adv Drug Deliv Rev. 2009.
PMID: 19138713
Review.
Item in Clipboard
A Phase I/IIa Safety and Efficacy Study of Nebulized Liposome-mediated Gene Therapy for Cystic Fibrosis Supports a Multidose Trial.
Alton EW, Boyd AC, Porteous DJ, Davies G, Davies JC, Griesenbach U, Higgins TE, Gill DR, Hyde SC, Innes JA; UK Cystic Fibrosis Gene Therapy Consortium *.
Alton EW, et al.
Am J Respir Crit Care Med. 2015 Dec 1;192(11):1389-92. doi: 10.1164/rccm.201506-1193LE.
Am J Respir Crit Care Med. 2015.
PMID: 26623687
Free PMC article.
Clinical Trial.
No abstract available.
Item in Clipboard
Assessment of CFTR function after gene transfer in vitro and in vivo.
Griesenbach U, Munkonge FM, Sumner-Jones S, Holder E, Smith SN, Boyd AC, Gill DR, Hyde SC, Porteous D, Alton EW; UK Cystic Fibrosis Gene Therapy Consortium.
Griesenbach U, et al.
Methods Mol Biol. 2008;433:229-42. doi: 10.1007/978-1-59745-237-3_14.
Methods Mol Biol. 2008.
PMID: 18679627
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