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2023 6
2024 4

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Page 1
The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1.
Romero R, Chu T, González-Robles TJ, Smith P, Xie Y, Kaur H, Yoder S, Zhao H, Mao C, Kang W, Pulina MV, Lawrence KE, Gopalan A, Zaidi S, Yoo K, Choi J, Fan N, Gerstner O, Karthaus WR, DeStanchina E, Ruggles KV, Westcott PMK, Chaligné R, Pe'er D, Sawyers CL. Romero R, et al. bioRxiv [Preprint]. 2024 Apr 11:2024.04.09.588557. doi: 10.1101/2024.04.09.588557. bioRxiv. 2024. PMID: 38645223 Free PMC article. Preprint.
Starfysh integrates spatial transcriptomic and histologic data to reveal heterogeneous tumor-immune hubs.
He S, Jin Y, Nazaret A, Shi L, Chen X, Rampersaud S, Dhillon BS, Valdez I, Friend LE, Fan JL, Park CY, Mintz RL, Lao YH, Carrera D, Fang KW, Mehdi K, Rohde M, McFaline-Figueroa JL, Blei D, Leong KW, Rudensky AY, Plitas G, Azizi E. He S, et al. Nat Biotechnol. 2024 Mar 21. doi: 10.1038/s41587-024-02173-8. Online ahead of print. Nat Biotechnol. 2024. PMID: 38514799
Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis.
Burdziak C, Alonso-Curbelo D, Walle T, Reyes J, Barriga FM, Haviv D, Xie Y, Zhao Z, Zhao CJ, Chen HA, Chaudhary O, Masilionis I, Choo ZN, Gao V, Luan W, Wuest A, Ho YJ, Wei Y, Quail DF, Koche R, Mazutis L, Chaligné R, Nawy T, Lowe SW, Pe'er D. Burdziak C, et al. Science. 2023 May 12;380(6645):eadd5327. doi: 10.1126/science.add5327. Epub 2023 May 12. Science. 2023. PMID: 37167403 Free PMC article.
Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies.
Glasner A, Rose SA, Sharma R, Gudjonson H, Chu T, Green JA, Rampersaud S, Valdez IK, Andretta ES, Dhillon BS, Schizas M, Dikiy S, Mendoza A, Hu W, Wang ZM, Chaudhary O, Xu T, Mazutis L, Rizzuto G, Quintanal-Villalonga A, Manoj P, de Stanchina E, Rudin CM, Pe'er D, Rudensky AY. Glasner A, et al. Nat Immunol. 2023 Jun;24(6):1020-1035. doi: 10.1038/s41590-023-01504-2. Epub 2023 May 1. Nat Immunol. 2023. PMID: 37127830 Free PMC article.
Metastasis.
Gerstberger S, Jiang Q, Ganesh K. Gerstberger S, et al. Cell. 2023 Apr 13;186(8):1564-1579. doi: 10.1016/j.cell.2023.03.003. Cell. 2023. PMID: 37059065 Free PMC article. Review.