U54 CA231649/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2020	1
2021	2
2022	4
2023	5
2024	0

1

Seed Becoming Soil: A New Paradigm of the Ewing Sarcoma Tumor Microenvironment.

Kuo C, Amatruda JF. Kuo C, et al. Clin Cancer Res. 2023 Dec 15;29(24):5002-5004. doi: 10.1158/1078-0432.CCR-23-2259. Clin Cancer Res. 2023. PMID: 37796143

2

Oxidative regulation of TDP-43 self-association by a β-to-α conformational switch.

Gu J, Zhou X, Sutherland L, Kato M, Jaczynska K, Rizo J, McKnight SL. Gu J, et al. Proc Natl Acad Sci U S A. 2023 Oct 10;120(41):e2311416120. doi: 10.1073/pnas.2311416120. Epub 2023 Oct 2. Proc Natl Acad Sci U S A. 2023. PMID: 37782781 Free PMC article.

3

Oxidative regulation of TDP-43 self-association by a β-to-α conformational switch.

Gu J, Zhou X, Sutherland L, Kato M, Jaczynska K, Rizo J, McKnight SL. Gu J, et al. bioRxiv [Preprint]. 2023 Aug 29:2023.08.29.555361. doi: 10.1101/2023.08.29.555361. bioRxiv. 2023. PMID: 37693418 Free PMC article. Updated. Preprint.

4

Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules.

Nguyen TP, Fang M, Kim J, Wang B, Lin E, Khivansara V, Barrows N, Rivera-Cancel G, Goralski M, Cervantes CL, Xie S, Peterson JM, Povedano JM, Antczak MI, Posner BA, Harvey CJB, Naughton BT, McFadden DG, Ready JM, De Brabander JK, Nijhawan D. Nguyen TP, et al. Cell Chem Biol. 2023 Nov 16;30(11):1453-1467.e8. doi: 10.1016/j.chembiol.2023.07.017. Epub 2023 Aug 21. Cell Chem Biol. 2023. PMID: 37607550

5

Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system.

Huang W, Li H, Kiselar J, Fink SP, Regmi S, Day A, Yuan Y, Chance M, Ready JM, Markowitz SD, Taylor DJ. Huang W, et al. Nat Commun. 2023 Feb 11;14(1):784. doi: 10.1038/s41467-023-36463-7. Nat Commun. 2023. PMID: 36774348 Free PMC article.

6

TK216 targets microtubules in Ewing sarcoma cells.

Povedano JM, Li V, Lake KE, Bai X, Rallabandi R, Kim J, Xie Y, De Brabander JK, McFadden DG. Povedano JM, et al. Cell Chem Biol. 2022 Aug 18;29(8):1325-1332.e4. doi: 10.1016/j.chembiol.2022.06.002. Epub 2022 Jul 7. Cell Chem Biol. 2022. PMID: 35803262 Free PMC article.

7

Mutations linked to neurological disease enhance self-association of low-complexity protein sequences.

Zhou X, Sumrow L, Tashiro K, Sutherland L, Liu D, Qin T, Kato M, Liszczak G, McKnight SL. Zhou X, et al. Science. 2022 Jul;377(6601):eabn5582. doi: 10.1126/science.abn5582. Epub 2022 Jul 1. Science. 2022. PMID: 35771920 Free PMC article.

8

Dysregulated heparan sulfate proteoglycan metabolism promotes Ewing sarcoma tumor growth.

Vasileva E, Warren M, Triche TJ, Amatruda JF. Vasileva E, et al. Elife. 2022 Mar 14;11:e69734. doi: 10.7554/eLife.69734. Elife. 2022. PMID: 35285802 Free PMC article.

9

How do protein domains of low sequence complexity work?

Kato M, Zhou X, McKnight SL. Kato M, et al. RNA. 2022 Jan;28(1):3-15. doi: 10.1261/rna.078990.121. Epub 2021 Oct 20. RNA. 2022. PMID: 34670847 Free PMC article. Review.

10

The low-complexity domain of the FUS RNA binding protein self-assembles via the mutually exclusive use of two distinct cross-β cores.

Kato M, McKnight SL. Kato M, et al. Proc Natl Acad Sci U S A. 2021 Oct 19;118(42):e2114412118. doi: 10.1073/pnas.2114412118. Proc Natl Acad Sci U S A. 2021. PMID: 34654750 Free PMC article.

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