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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
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2010 | 2 |
2011 | 2 |
2024 | 0 |
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Structure-guided lead optimization of triazolopyrimidine-ring substituents identifies potent Plasmodium falciparum dihydroorotate dehydrogenase inhibitors with clinical candidate potential.
J Med Chem. 2011 Aug 11;54(15):5540-61. doi: 10.1021/jm200592f. Epub 2011 Jul 14.
J Med Chem. 2011.
PMID: 21696174
Free PMC article.
Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice.
Gujjar R, El Mazouni F, White KL, White J, Creason S, Shackleford DM, Deng X, Charman WN, Bathurst I, Burrows J, Floyd DM, Matthews D, Buckner FS, Charman SA, Phillips MA, Rathod PK.
Gujjar R, et al.
J Med Chem. 2011 Jun 9;54(11):3935-49. doi: 10.1021/jm200265b. Epub 2011 May 12.
J Med Chem. 2011.
PMID: 21517059
Free PMC article.
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Chemical genetics of Plasmodium falciparum.
Guiguemde WA, Shelat AA, Bouck D, Duffy S, Crowther GJ, Davis PH, Smithson DC, Connelly M, Clark J, Zhu F, Jiménez-Díaz MB, Martinez MS, Wilson EB, Tripathi AK, Gut J, Sharlow ER, Bathurst I, El Mazouni F, Fowble JW, Forquer I, McGinley PL, Castro S, Angulo-Barturen I, Ferrer S, Rosenthal PJ, Derisi JL, Sullivan DJ, Lazo JS, Roos DS, Riscoe MK, Phillips MA, Rathod PK, Van Voorhis WC, Avery VM, Guy RK.
Guiguemde WA, et al.
Nature. 2010 May 20;465(7296):311-5. doi: 10.1038/nature09099.
Nature. 2010.
PMID: 20485428
Free PMC article.
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Plasmodium dihydroorotate dehydrogenase: a promising target for novel anti-malarial chemotherapy.
Phillips MA, Rathod PK.
Phillips MA, et al.
Infect Disord Drug Targets. 2010 Jun;10(3):226-39. doi: 10.2174/187152610791163336.
Infect Disord Drug Targets. 2010.
PMID: 20334617
Free PMC article.
Review.
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