Tzvetkov MV - Search Results

1

The Effect of Capsule-in-Capsule Combinations on In Vivo Disintegration in Human Volunteers: A Combined Imaging and Salivary Tracer Study.

Rump A, Weiss FN, Schulz L, Kromrey ML, Scheuch E, Tzvetkov MV, White T, Durkee S, Judge KW, Jannin V, Bellamine A, Weitschies W, Grimm M. Rump A, et al. Among authors: tzvetkov mv. Pharmaceutics. 2021 Nov 25;13(12):2002. doi: 10.3390/pharmaceutics13122002. Pharmaceutics. 2021. PMID: 34959284 Free PMC article.

2

Comparison of In Vitro and In Vivo Results Using the GastroDuo and the Salivary Tracer Technique: Immediate Release Dosage Forms under Fasting Conditions.

Sager M, Schick P, Mischek M, Schulze C, Hasan M, Kromrey ML, Benameur H, Wendler M, Tzvetkov MV, Weitschies W, Koziolek M. Sager M, et al. Among authors: tzvetkov mv. Pharmaceutics. 2019 Dec 7;11(12):659. doi: 10.3390/pharmaceutics11120659. Pharmaceutics. 2019. PMID: 31817867 Free PMC article.

3

Combined Application of MRI and the Salivary Tracer Technique to Determine the in Vivo Disintegration Time of Immediate Release Formulation Administered to Healthy, Fasted Subjects.

Sager M, Grimm M, Jedamzik P, Merdivan S, Kromrey ML, Hasan M, Koziolek M, Tzvetkov MV, Weitschies W. Sager M, et al. Among authors: tzvetkov mv. Mol Pharm. 2019 Apr 1;16(4):1782-1786. doi: 10.1021/acs.molpharmaceut.8b01320. Epub 2019 Mar 8. Mol Pharm. 2019. PMID: 30821987

4

In vivo characterization of enTRinsic™ drug delivery technology capsule after intake in fed state: A cross-validation approach using salivary tracer technique in comparison to MRI.

Sager M, Grimm M, Aude P, Schick P, Merdivan S, Hasan M, Kromrey ML, Sivert A, Benameur H, Koziolek M, Tzvetkov MV, Weitschies W. Sager M, et al. Among authors: tzvetkov mv. J Control Release. 2019 Nov 10;313:24-32. doi: 10.1016/j.jconrel.2019.10.023. Epub 2019 Oct 15. J Control Release. 2019. PMID: 31626859 Clinical Trial.

5

Pharmacokinetic Drug-Drug Interactions Between Trospium Chloride and Ranitidine Substrates of Organic Cation Transporters in Healthy Human Subjects.

Abebe BT, Weiss M, Modess C, Tadken T, Wegner D, Meyer MJ, Schwantes U, Neumeister C, Scheuch E, Schulz HU, Tzvetkov M, Siegmund W. Abebe BT, et al. J Clin Pharmacol. 2020 Mar;60(3):312-323. doi: 10.1002/jcph.1523. Epub 2019 Sep 22. J Clin Pharmacol. 2020. PMID: 31542894

6

Effects of genetic polymorphisms on the OCT1 and OCT2-mediated uptake of ranitidine.

Meyer MJ, Seitz T, Brockmöller J, Tzvetkov MV. Meyer MJ, et al. Among authors: tzvetkov mv. PLoS One. 2017 Dec 13;12(12):e0189521. doi: 10.1371/journal.pone.0189521. eCollection 2017. PLoS One. 2017. PMID: 29236753 Free PMC article.

7

Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1.

Meyer MJ, Neumann VE, Friesacher HR, Zdrazil B, Brockmöller J, Tzvetkov MV. Meyer MJ, et al. Among authors: tzvetkov mv. J Med Chem. 2019 Nov 14;62(21):9890-9905. doi: 10.1021/acs.jmedchem.9b01301. Epub 2019 Nov 4. J Med Chem. 2019. PMID: 31597043

8

Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-Facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake.

Gorboulev V, Rehman S, Albert CM, Roth U, Meyer MJ, Tzvetkov MV, Mueller TD, Koepsell H. Gorboulev V, et al. Among authors: tzvetkov mv. Mol Pharmacol. 2018 Apr;93(4):402-415. doi: 10.1124/mol.117.110767. Epub 2018 Jan 16. Mol Pharmacol. 2018. PMID: 29339398

9

OCT1 Polyspecificity-Friend or Foe?

Meyer MJ, Tzvetkov MV. Meyer MJ, et al. Among authors: tzvetkov mv. Front Pharmacol. 2021 Jun 2;12:698153. doi: 10.3389/fphar.2021.698153. eCollection 2021. Front Pharmacol. 2021. PMID: 34149437 Free PMC article. No abstract available.

10

Cloning and Functional Characterization of Dog OCT1 and OCT2: Another Step in Exploring Species Differences in Organic Cation Transporters.

Meyer MJ, Falk S, Römer S, Prinzinger C, Tacke S, Geyer J, Simm S, Tzvetkov MV. Meyer MJ, et al. Among authors: tzvetkov mv. Int J Mol Sci. 2022 May 4;23(9):5100. doi: 10.3390/ijms23095100. Int J Mol Sci. 2022. PMID: 35563491 Free PMC article.

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