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Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing.
Gilmour BC, Gudmundsrud R, Frank J, Hov A, Lautrup S, Aman Y, Røsjø H, Brenner C, Ziegler M, Tysnes OB, Tzoulis C, Omland T, Søraas A, Holmøy T, Bergersen LH, Storm-Mathisen J, Nilsen H, Fang EF. Gilmour BC, et al. Among authors: tzoulis c. Mech Ageing Dev. 2020 Mar;186:111208. doi: 10.1016/j.mad.2020.111208. Epub 2020 Jan 15. Mech Ageing Dev. 2020. PMID: 31953124 Free article. Review.
HTRA2 p.G399S in Parkinson disease, essential tremor, and tremulous cervical dystonia.
Tzoulis C, Zayats T, Knappskog PM, Müller B, Larsen JP, Tysnes OB, Bindoff LA, Johansson S, Haugarvoll K. Tzoulis C, et al. Proc Natl Acad Sci U S A. 2015 May 5;112(18):E2268. doi: 10.1073/pnas.1503105112. Epub 2015 Mar 30. Proc Natl Acad Sci U S A. 2015. PMID: 25825781 Free PMC article. No abstract available.
Ultradeep mapping of neuronal mitochondrial deletions in Parkinson's disease.
Nido GS, Dölle C, Flønes I, Tuppen HA, Alves G, Tysnes OB, Haugarvoll K, Tzoulis C. Nido GS, et al. Among authors: tzoulis c. Neurobiol Aging. 2018 Mar;63:120-127. doi: 10.1016/j.neurobiolaging.2017.10.024. Epub 2017 Dec 8. Neurobiol Aging. 2018. PMID: 29257976 Free article.
Neuronal complex I deficiency occurs throughout the Parkinson's disease brain, but is not associated with neurodegeneration or mitochondrial DNA damage.
Flønes IH, Fernandez-Vizarra E, Lykouri M, Brakedal B, Skeie GO, Miletic H, Lilleng PK, Alves G, Tysnes OB, Haugarvoll K, Dölle C, Zeviani M, Tzoulis C. Flønes IH, et al. Among authors: tzoulis c. Acta Neuropathol. 2018 Mar;135(3):409-425. doi: 10.1007/s00401-017-1794-7. Epub 2017 Dec 21. Acta Neuropathol. 2018. PMID: 29270838
Association of glucocerebrosidase polymorphisms and mutations with dementia in incident Parkinson's disease.
Lunde KA, Chung J, Dalen I, Pedersen KF, Linder J, Domellöf ME, Elgh E, Macleod AD, Tzoulis C, Larsen JP, Tysnes OB, Forsgren L, Counsell CE, Alves G, Maple-Grødem J. Lunde KA, et al. Among authors: tzoulis c. Alzheimers Dement. 2018 Oct;14(10):1293-1301. doi: 10.1016/j.jalz.2018.04.006. Epub 2018 May 21. Alzheimers Dement. 2018. PMID: 29792872
97 results