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Glycosylation-dependent activation of epithelial sodium channel by solnatide.
Shabbir W, Tzotzos S, Bedak M, Aufy M, Willam A, Kraihammer M, Holzner A, Czikora I, Scherbaum-Hazemi P, Fischer H, Pietschmann H, Fischer B, Lucas R, Lemmens-Gruber R. Shabbir W, et al. Biochem Pharmacol. 2015 Dec 15;98(4):740-53. doi: 10.1016/j.bcp.2015.08.003. Epub 2015 Aug 5. Biochem Pharmacol. 2015. PMID: 26254591
The Lectin-like Domain of TNF Increases ENaC Open Probability through a Novel Site at the Interface between the Second Transmembrane and C-terminal Domains of the α-Subunit.
Lucas R, Yue Q, Alli A, Duke BJ, Al-Khalili O, Thai TL, Hamacher J, Sridhar S, Lebedyeva I, Su H, Tzotzos S, Fischer B, Gameiro AF, Loose M, Chakraborty T, Shabbir W, Aufy M, Lemmens-Gruber R, Eaton DC, Czikora I. Lucas R, et al. J Biol Chem. 2016 Nov 4;291(45):23440-23451. doi: 10.1074/jbc.M116.718163. Epub 2016 Sep 19. J Biol Chem. 2016. PMID: 27645999 Free PMC article.
TNF Lectin-Like Domain Restores Epithelial Sodium Channel Function in Frameshift Mutants Associated with Pseudohypoaldosteronism Type 1B.
Willam A, Aufy M, Tzotzos S, El-Malazi D, Poser F, Wagner A, Unterköfler B, Gurmani D, Martan D, Iqbal SM, Fischer B, Fischer H, Pietschmann H, Czikora I, Lucas R, Lemmens-Gruber R, Shabbir W. Willam A, et al. Front Immunol. 2017 May 29;8:601. doi: 10.3389/fimmu.2017.00601. eCollection 2017. Front Immunol. 2017. PMID: 28611771 Free PMC article.
Conformational ensemble of the TNF-derived peptide solnatide in solution.
Martin-Malpartida P, Arrastia-Casado S, Farrera-Sinfreu J, Lucas R, Fischer H, Fischer B, Eaton DC, Tzotzos S, Macias MJ. Martin-Malpartida P, et al. Comput Struct Biotechnol J. 2022 Apr 27;20:2082-2090. doi: 10.1016/j.csbj.2022.04.031. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 35601958 Free PMC article.
12 results