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Chromosome 11q loss and MYCN amplification demonstrate synthetic lethality with checkpoint kinase 1 inhibition in neuroblastoma.
Keller KM, Eleveld TF, Schild L, van den Handel K, van den Boogaard M, Amo-Addae V, Eising S, Ober K, Koopmans B, Looijenga L, Tytgat GAM, Ylstra B, Molenaar JJ, Dolman MEM, van Hooff SR. Keller KM, et al. Among authors: tytgat gam. Front Oncol. 2022 Sep 27;12:929123. doi: 10.3389/fonc.2022.929123. eCollection 2022. Front Oncol. 2022. PMID: 36237330 Free PMC article.
Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors.
Calandrini C, van Hooff SR, Paassen I, Ayyildiz D, Derakhshan S, Dolman MEM, Langenberg KPS, van de Ven M, de Heus C, Liv N, Kool M, de Krijger RR, Tytgat GAM, van den Heuvel-Eibrink MM, Molenaar JJ, Drost J. Calandrini C, et al. Among authors: tytgat gam. Cell Rep. 2021 Aug 24;36(8):109568. doi: 10.1016/j.celrep.2021.109568. Cell Rep. 2021. PMID: 34433038 Free article.
Mesenchymal Neuroblastoma Cells Are Undetected by Current mRNA Marker Panels: The Development of a Specific Neuroblastoma Mesenchymal Minimal Residual Disease Panel.
van Wezel EM, van Zogchel LMJ, van Wijk J, Timmerman I, Vo NK, Zappeij-Kannegieter L, deCarolis B, Simon T, van Noesel MM, Molenaar JJ, van Groningen T, Versteeg R, Caron HN, van der Schoot CE, Koster J, van Nes J, Tytgat GAM. van Wezel EM, et al. Among authors: tytgat gam. JCO Precis Oncol. 2019 Oct 3;3:PO.18.00413. doi: 10.1200/PO.18.00413. eCollection 2019. JCO Precis Oncol. 2019. PMID: 34036221 Free PMC article.
G-CSF as a suitable alternative to GM-CSF to boost dinutuximab-mediated neutrophil cytotoxicity in neuroblastoma treatment.
Martinez Sanz P, van Rees DJ, van Zogchel LMJ, Klein B, Bouti P, Olsman H, Schornagel K, Kok I, Sunak A, Leeuwenburg K, Timmerman I, Dierselhuis MP, Kholosy WM, Molenaar JJ, van Bruggen R, van den Berg TK, Kuijpers TW, Matlung HL, Tytgat GAM, Franke K. Martinez Sanz P, et al. Among authors: tytgat gam. J Immunother Cancer. 2021 May;9(5):e002259. doi: 10.1136/jitc-2020-002259. J Immunother Cancer. 2021. PMID: 34049929 Free PMC article.
98 results