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p63 uses a switch-like mechanism to set the threshold for induction of apoptosis.
Gebel J, Tuppi M, Chaikuad A, Hötte K, Schröder M, Schulz L, Löhr F, Gutfreund N, Finke F, Henrich E, Mezhyrova J, Lehnert R, Pampaloni F, Hummer G, Stelzer EHK, Knapp S, Dötsch V. Gebel J, et al. Among authors: tuppi m. Nat Chem Biol. 2020 Oct;16(10):1078-1086. doi: 10.1038/s41589-020-0600-3. Epub 2020 Jul 27. Nat Chem Biol. 2020. PMID: 32719556
Control mechanisms in germ cells mediated by p53 family proteins.
Gebel J, Tuppi M, Krauskopf K, Coutandin D, Pitzius S, Kehrloesser S, Osterburg C, Dötsch V. Gebel J, et al. Among authors: tuppi m. J Cell Sci. 2017 Aug 9:jcs.204859. doi: 10.1242/jcs.204859. Online ahead of print. J Cell Sci. 2017. PMID: 28794013 Review.
CHK2 sets the stage for CK1 in oocyte quality control.
Kehrloesser S, Tuppi M, Dötsch V. Kehrloesser S, et al. Among authors: tuppi m. Cell Death Differ. 2018 Jun;25(6):1007-1009. doi: 10.1038/s41418-018-0107-6. Cell Death Differ. 2018. PMID: 29666471 Free PMC article. No abstract available.
Cell cycle arrest in mitosis promotes interferon-induced necroptosis.
Frank T, Tuppi M, Hugle M, Dötsch V, van Wijk SJL, Fulda S. Frank T, et al. Among authors: tuppi m. Cell Death Differ. 2019 Oct;26(10):2046-2060. doi: 10.1038/s41418-019-0298-5. Epub 2019 Feb 11. Cell Death Differ. 2019. PMID: 30742091 Free PMC article.
DNA Damaged Induced Cell Death in Oocytes.
Gebel J, Tuppi M, Sänger N, Schumacher B, Dötsch V. Gebel J, et al. Among authors: tuppi m. Molecules. 2020 Dec 3;25(23):5714. doi: 10.3390/molecules25235714. Molecules. 2020. PMID: 33287328 Free PMC article. Review.
14 results