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An exercise-inducible metabolite that suppresses feeding and obesity.
Li VL, He Y, Contrepois K, Liu H, Kim JT, Wiggenhorn AL, Tanzo JT, Tung AS, Lyu X, Zushin PH, Jansen RS, Michael B, Loh KY, Yang AC, Carl CS, Voldstedlund CT, Wei W, Terrell SM, Moeller BC, Arthur RM, Wallis GA, van de Wetering K, Stahl A, Kiens B, Richter EA, Banik SM, Snyder MP, Xu Y, Long JZ. Li VL, et al. Among authors: tung as. Nature. 2022 Jun;606(7915):785-790. doi: 10.1038/s41586-022-04828-5. Epub 2022 Jun 15. Nature. 2022. PMID: 35705806 Free PMC article.
Lac-Phe mediates the effects of metformin on food intake and body weight.
Xiao S, Li VL, Lyu X, Chen X, Wei W, Abbasi F, Knowles JW, Tung AS, Deng S, Tiwari G, Shi X, Zheng S, Farrell L, Chen ZZ, Taylor KD, Guo X, Goodarzi MO, Wood AC, Chen YI, Lange LA, Rich SS, Rotter JI, Clish CB, Tahir UA, Gerszten RE, Benson MD, Long JZ. Xiao S, et al. Among authors: tung as. Nat Metab. 2024 Apr;6(4):659-669. doi: 10.1038/s42255-024-00999-9. Epub 2024 Mar 18. Nat Metab. 2024. PMID: 38499766
SLC17 transporters mediate renal excretion of Lac-Phe in mice and humans.
Li VL, Xiao S, Schlosser P, Scherer N, Wiggenhorn AL, Spaas J, Tung AS, Karoly ED, Köttgen A, Long JZ. Li VL, et al. Among authors: tung as. bioRxiv [Preprint]. 2024 Apr 18:2024.04.18.589815. doi: 10.1101/2024.04.18.589815. bioRxiv. 2024. PMID: 38659895 Free PMC article. Preprint.
42 results