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The HIV capsid mimics karyopherin engagement of FG-nucleoporins.
Dickson CF, Hertel S, Tuckwell AJ, Li N, Ruan J, Al-Izzi SC, Ariotti N, Sierecki E, Gambin Y, Morris RG, Towers GJ, Böcking T, Jacques DA. Dickson CF, et al. Among authors: tuckwell aj. Nature. 2024 Feb;626(8000):836-842. doi: 10.1038/s41586-023-06969-7. Epub 2024 Jan 24. Nature. 2024. PMID: 38267582 Free PMC article.
Recognition of HIV-1 capsid by PQBP1 licenses an innate immune sensing of nascent HIV-1 DNA.
Yoh SM, Mamede JI, Lau D, Ahn N, Sánchez-Aparicio MT, Temple J, Tuckwell A, Fuchs NV, Cianci GC, Riva L, Curry H, Yin X, Gambut S, Simons LM, Hultquist JF, König R, Xiong Y, García-Sastre A, Böcking T, Hope TJ, Chanda SK. Yoh SM, et al. Among authors: tuckwell a. Mol Cell. 2022 Aug 4;82(15):2871-2884.e6. doi: 10.1016/j.molcel.2022.06.010. Epub 2022 Jul 8. Mol Cell. 2022. PMID: 35809572 Free PMC article.
Rapid HIV-1 Capsid Interaction Screening Using Fluorescence Fluctuation Spectroscopy.
Lau D, Walsh JC, Dickson CF, Tuckwell A, Stear JH, Hunter DJB, Bhumkar A, Shah V, Turville SG, Sierecki E, Gambin Y, Böcking T, Jacques DA. Lau D, et al. Among authors: tuckwell a. Anal Chem. 2021 Mar 2;93(8):3786-3793. doi: 10.1021/acs.analchem.0c04250. Epub 2021 Feb 16. Anal Chem. 2021. PMID: 33593049