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A 52-week placebo-controlled trial of evolocumab in hyperlipidemia.
Blom DJ, Hala T, Bolognese M, Lillestol MJ, Toth PD, Burgess L, Ceska R, Roth E, Koren MJ, Ballantyne CM, Monsalvo ML, Tsirtsonis K, Kim JB, Scott R, Wasserman SM, Stein EA; DESCARTES Investigators. Blom DJ, et al. Among authors: tsirtsonis k. N Engl J Med. 2014 May 8;370(19):1809-19. doi: 10.1056/NEJMoa1316222. Epub 2014 Mar 29. N Engl J Med. 2014. PMID: 24678979 Free article. Clinical Trial.
A First-in-Human Study of AMG 986, a Novel Apelin Receptor Agonist, in Healthy Subjects and Heart Failure Patients.
Winkle P, Goldsmith S, Koren MJ, Lepage S, Hellawell J, Trivedi A, Tsirtsonis K, Abbasi SA, Kaufman A, Troughton R, Voors A, Hulot JS, Donal E, Kazemi N, Neutel J. Winkle P, et al. Among authors: tsirtsonis k. Cardiovasc Drugs Ther. 2023 Aug;37(4):743-755. doi: 10.1007/s10557-022-07328-w. Epub 2022 Apr 23. Cardiovasc Drugs Ther. 2023. PMID: 35460392 Clinical Trial.
A first step towards best practice recommendations for the design and statistical analyses of pragmatic clinical trials: A modified Delphi approach.
Palin V, Van Staa TP, Steels S, Troxel AB, Groenwold RHH, MacDonald TM, Torgerson D, Faries D, Mancini P, Ouwens M, Frith LJ, Tsirtsonis K, MacLennan G, Nordon C; GetReal Initiative. Palin V, et al. Among authors: tsirtsonis k. Br J Clin Pharmacol. 2022 Dec;88(12):5183-5201. doi: 10.1111/bcp.15441. Epub 2022 Jul 1. Br J Clin Pharmacol. 2022. PMID: 35701368 Free article.