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Fentanyl-Induced Block of hERG Channels Is Exacerbated by Hypoxia, Hypokalemia, Alkalosis, and the Presence of hERG1b.
Mol Pharmacol. 2020 Oct;98(4):508-517. doi: 10.1124/mol.119.119271. Epub 2020 Apr 22.
Mol Pharmacol. 2020.
PMID: 32321735
Blockade of the Human Ether A-Go-Go-Related Gene (hERG) Potassium Channel by Fentanyl.
Tschirhart JN, Li W, Guo J, Zhang S.
Tschirhart JN, et al.
Mol Pharmacol. 2019 Apr;95(4):386-397. doi: 10.1124/mol.118.114751. Epub 2019 Jan 21.
Mol Pharmacol. 2019.
PMID: 30665971
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Differential Regulation of Human Ether-à-Go-Go-Related Gene (hERG) Current and Expression by Activation of Protein Kinase C.
Sutherland-Deveen ME, Wang T, Lamothe SM, Tschirhart JN, Guo J, Li W, Yang T, Du Y, Zhang S.
Sutherland-Deveen ME, et al. Among authors: tschirhart jn.
Mol Pharmacol. 2019 Jul;96(1):1-12. doi: 10.1124/mol.118.115188. Epub 2019 Apr 23.
Mol Pharmacol. 2019.
PMID: 31015282
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The N terminus and transmembrane segment S1 of Kv1.5 can coassemble with the rest of the channel independently of the S1-S2 linkage.
Lamothe SM, Hogan-Cann AE, Li W, Guo J, Yang T, Tschirhart JN, Zhang S.
Lamothe SM, et al. Among authors: tschirhart jn.
J Biol Chem. 2018 Oct 5;293(40):15347-15358. doi: 10.1074/jbc.RA118.004065. Epub 2018 Aug 17.
J Biol Chem. 2018.
PMID: 30121572
Free PMC article.
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