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Methotrexate inhibition of SARS-CoV-2 entry, infection and inflammation revealed by bioinformatics approach and a hamster model.
Chen YT, Chang YH, Pathak N, Tzou SC, Luo YC, Hsu YC, Li TN, Lee JY, Chen YC, Huang YW, Yang HJ, Hsu NY, Tsai HP, Chang TY, Hsu SC, Liu PC, Chin YF, Lin WC, Yang CM, Wu HL, Lee CY, Hsu HL, Liu YC, Chu JW, Wang LH, Wang JY, Huang CH, Lin CH, Hsieh PS, Wu Lee YH, Hung YJ, Yang JM. Chen YT, et al. Among authors: tsai hp. Front Immunol. 2022 Dec 21;13:1080897. doi: 10.3389/fimmu.2022.1080897. eCollection 2022. Front Immunol. 2022. PMID: 36618412 Free PMC article.
BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase inhibitor, inhibits SARS-CoV-2 variants of concern and exerts synergistic antiviral activity in combination with remdesivir.
Tang W-F, Chang Y-H, Lin C-C, Jheng J-R, Hsieh C-F, Chin Y-F, Chang T-Y, Lee J-C, Liang P-H, Lin C-Y, Lin G-H, Cai J-Y, Chen Y-L, Chen Y-S, Tsai S-K, Liu P-C, Yang C-M, Shadbahr T, Tang J, Hsu Y-L, Huang C-H, Wang L-Y, Chen CC, Kau J-H, Hung Y-J, Lee H-Y, Wang W-C, Tsai H-P, Horng J-T. Tang W-F, et al. Antimicrob Agents Chemother. 2024 Apr 3;68(4):e0095623. doi: 10.1128/aac.00956-23. Epub 2024 Mar 6. Antimicrob Agents Chemother. 2024. PMID: 38446062 Free PMC article.
Epicatechin isolated from Tripterygium wilfordii extract reduces tau-GFP-induced neurotoxicity in zebrafish embryo through the activation of Nrf2.
Wu BK, Yuan RY, Chang YP, Lien HW, Chen TS, Chien HC, Tong TS, Tsai HP, Fang CL, Liao YF, Chang CC, Chen RP, Huang CJ. Wu BK, et al. Among authors: tsai hp. Biochem Biophys Res Commun. 2016 Aug 19;477(2):283-9. doi: 10.1016/j.bbrc.2016.06.058. Epub 2016 Jun 11. Biochem Biophys Res Commun. 2016. PMID: 27301640
172 results