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Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity.
Sum E, Rapp M, Fröbel P, Le Clech M, Dürr H, Giusti AM, Perro M, Speziale D, Kunz L, Menietti E, Brünker P, Hopfer U, Lechmann M, Sobieniecki A, Appelt B, Adelfio R, Nicolini V, Freimoser-Grundschober A, Jordaan W, Labiano S, Weber F, Emrich T, Christen F, Essig B, Romero P, Trumpfheller C, Umaña P. Sum E, et al. Among authors: trumpfheller c. Clin Cancer Res. 2021 Jul 15;27(14):4036-4053. doi: 10.1158/1078-0432.CCR-20-4001. Epub 2021 Mar 26. Clin Cancer Res. 2021. PMID: 33771854
CD40 Agonist Targeted to Fibroblast Activation Protein α Synergizes with Radiotherapy in Murine HPV-Positive Head and Neck Tumors.
Labiano S, Roh V, Godfroid C, Hiou-Feige A, Romero J, Sum E, Rapp M, Boivin G, Wyss T, Simon C, Bourhis J, Umaña P, Trumpfheller C, Tolstonog GV, Vozenin MC, Romero P. Labiano S, et al. Among authors: trumpfheller c. Clin Cancer Res. 2021 Jul 15;27(14):4054-4065. doi: 10.1158/1078-0432.CCR-20-4717. Epub 2021 Apr 26. Clin Cancer Res. 2021. PMID: 33903200
Combinations of Toll-like receptor 8 agonist TL8-506 activate human tumor-derived dendritic cells.
He M, Soni B, Schwalie PC, Hüsser T, Waltzinger C, De Silva D, Prinz Y, Krümpelmann L, Calabro S, Matos I, Trumpfheller C, Bacac M, Umaña P, Levesque MP, Dummer R, van den Broek M, Gasser S. He M, et al. Among authors: trumpfheller c. J Immunother Cancer. 2022 Jun;10(6):e004268. doi: 10.1136/jitc-2021-004268. J Immunother Cancer. 2022. PMID: 35688559 Free PMC article.
Microfluidic Squeezing Enables MHC Class I Antigen Presentation by Diverse Immune Cells to Elicit CD8+ T Cell Responses with Antitumor Activity.
Booty MG, Hlavaty KA, Stockmann A, Ozay EI, Smith C, Tian L, How E, Subramanya D, Venkitaraman A, Yee C, Pryor O, Volk K, Blagovic K, Vicente-Suarez I, Yarar D, Myint M, Merino A, Chow J, Abdeljawad T, An H, Liu S, Mao S, Heimann M, Talarico L, Jacques MK, Chong E, Pomerance L, Gonzalez JT, von Andrian UH, Jensen KF, Langer R, Knoetgen H, Trumpfheller C, Umaña P, Bernstein H, Sharei A, Loughhead SM. Booty MG, et al. Among authors: trumpfheller c. J Immunol. 2022 Feb 15;208(4):929-940. doi: 10.4049/jimmunol.2100656. Epub 2022 Jan 28. J Immunol. 2022. PMID: 35091434 Free PMC article.
Dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin/CD209 is abundant on macrophages in the normal human lymph node and is not required for dendritic cell stimulation of the mixed leukocyte reaction.
Granelli-Piperno A, Pritsker A, Pack M, Shimeliovich I, Arrighi JF, Park CG, Trumpfheller C, Piguet V, Moran TM, Steinman RM. Granelli-Piperno A, et al. Among authors: trumpfheller c. J Immunol. 2005 Oct 1;175(7):4265-73. doi: 10.4049/jimmunol.175.7.4265. J Immunol. 2005. PMID: 16177066 Free PMC article.
39 results