Troppmair J - Search Results

1

BRAF inhibitors promote intermediate BRAF(V600E) conformations and binary interactions with activated RAS.

Röck R, Mayrhofer JE, Torres-Quesada O, Enzler F, Raffeiner A, Raffeiner P, Feichtner A, Huber RG, Koide S, Taylor SS, Troppmair J, Stefan E. Röck R, et al. Among authors: troppmair j. Sci Adv. 2019 Aug 14;5(8):eaav8463. doi: 10.1126/sciadv.aav8463. eCollection 2019 Aug. Sci Adv. 2019. PMID: 31453322 Free PMC article.

2

Isolation of a novel thioflavin S-derived compound that inhibits BAG-1-mediated protein interactions and targets BRAF inhibitor-resistant cell lines.

Enthammer M, Papadakis ES, Salomé Gachet M, Deutsch M, Schwaiger S, Koziel K, Ashraf MI, Khalid S, Wolber G, Packham G, Cutress RI, Stuppner H, Troppmair J. Enthammer M, et al. Among authors: troppmair j. Mol Cancer Ther. 2013 Nov;12(11):2400-14. doi: 10.1158/1535-7163.MCT-13-0142. Epub 2013 Sep 18. Mol Cancer Ther. 2013. PMID: 24048738

3

Targeting the Architecture of Deregulated Protein Complexes in Cancer.

Stefan E, Troppmair J, Bister K. Stefan E, et al. Among authors: troppmair j. Adv Protein Chem Struct Biol. 2018;111:101-132. doi: 10.1016/bs.apcsb.2017.07.001. Epub 2017 Aug 18. Adv Protein Chem Struct Biol. 2018. PMID: 29459029 Review.

4

Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies.

Mayrhofer JE, Enzler F, Feichtner A, Röck R, Fleischmann J, Raffeiner A, Tschaikner P, Ogris E, Huber RG, Hartl M, Schneider R, Troppmair J, Torres-Quesada O, Stefan E. Mayrhofer JE, et al. Among authors: troppmair j. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31105-31113. doi: 10.1073/pnas.2012150117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229534 Free PMC article.

5

The Role of BRAF in Metastatic Colorectal Carcinoma-Past, Present, and Future.

Djanani A, Eller S, Öfner D, Troppmair J, Maglione M. Djanani A, et al. Among authors: troppmair j. Int J Mol Sci. 2020 Nov 26;21(23):9001. doi: 10.3390/ijms21239001. Int J Mol Sci. 2020. PMID: 33256240 Free PMC article. Review.

6

Raf and the road to cell survival: a tale of bad spells, ring bearers and detours.

Troppmair J, Rapp UR. Troppmair J, et al. Biochem Pharmacol. 2003 Oct 15;66(8):1341-5. doi: 10.1016/s0006-2952(03)00483-0. Biochem Pharmacol. 2003. PMID: 14555207 Review.

7

The oxidoreductase p66Shc acts as tumor suppressor in BRAFV600E-transformed cells.

Furlan T, Khalid S, Nguyen AV, Günther J, Troppmair J. Furlan T, et al. Among authors: troppmair j. Mol Oncol. 2018 Jun;12(6):869-882. doi: 10.1002/1878-0261.12199. Epub 2018 May 5. Mol Oncol. 2018. PMID: 29624862 Free PMC article.

8

Regulating cell survival by controlling cellular energy production: novel functions for ancient signaling pathways?

Kuznetsov AV, Janakiraman M, Margreiter R, Troppmair J. Kuznetsov AV, et al. Among authors: troppmair j. FEBS Lett. 2004 Nov 5;577(1-2):1-4. doi: 10.1016/j.febslet.2004.10.021. FEBS Lett. 2004. PMID: 15527752 Free article. Review.

9

Signaling through RAS-RAF-MEK-ERK: from basics to bedside.

Zebisch A, Czernilofsky AP, Keri G, Smigelskaite J, Sill H, Troppmair J. Zebisch A, et al. Among authors: troppmair j. Curr Med Chem. 2007;14(5):601-23. doi: 10.2174/092986707780059670. Curr Med Chem. 2007. PMID: 17346150 Review.

10

Survival signaling by C-RAF: mitochondrial reactive oxygen species and Ca2+ are critical targets.

Kuznetsov AV, Smigelskaite J, Doblander C, Janakiraman M, Hermann M, Wurm M, Scheidl SF, Sucher R, Deutschmann A, Troppmair J. Kuznetsov AV, et al. Among authors: troppmair j. Mol Cell Biol. 2008 Apr;28(7):2304-13. doi: 10.1128/MCB.00683-07. Epub 2008 Jan 22. Mol Cell Biol. 2008. PMID: 18212057 Free PMC article.

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