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A dysbiotic microbiome triggers TH17 cells to mediate oral mucosal immunopathology in mice and humans.
Dutzan N, Kajikawa T, Abusleme L, Greenwell-Wild T, Zuazo CE, Ikeuchi T, Brenchley L, Abe T, Hurabielle C, Martin D, Morell RJ, Freeman AF, Lazarevic V, Trinchieri G, Diaz PI, Holland SM, Belkaid Y, Hajishengallis G, Moutsopoulos NM. Dutzan N, et al. Among authors: trinchieri g. Sci Transl Med. 2018 Oct 17;10(463):eaat0797. doi: 10.1126/scitranslmed.aat0797. Sci Transl Med. 2018. PMID: 30333238 Free PMC article. Clinical Trial.
Compartmentalized control of skin immunity by resident commensals.
Naik S, Bouladoux N, Wilhelm C, Molloy MJ, Salcedo R, Kastenmuller W, Deming C, Quinones M, Koo L, Conlan S, Spencer S, Hall JA, Dzutsev A, Kong H, Campbell DJ, Trinchieri G, Segre JA, Belkaid Y. Naik S, et al. Among authors: trinchieri g. Science. 2012 Aug 31;337(6098):1115-9. doi: 10.1126/science.1225152. Epub 2012 Jul 26. Science. 2012. PMID: 22837383 Free PMC article.
Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment.
Iida N, Dzutsev A, Stewart CA, Smith L, Bouladoux N, Weingarten RA, Molina DA, Salcedo R, Back T, Cramer S, Dai RM, Kiu H, Cardone M, Naik S, Patri AK, Wang E, Marincola FM, Frank KM, Belkaid Y, Trinchieri G, Goldszmid RS. Iida N, et al. Among authors: trinchieri g. Science. 2013 Nov 22;342(6161):967-70. doi: 10.1126/science.1240527. Science. 2013. PMID: 24264989 Free PMC article.
Bone-Marrow-Resident NK Cells Prime Monocytes for Regulatory Function during Infection.
Askenase MH, Han SJ, Byrd AL, Morais da Fonseca D, Bouladoux N, Wilhelm C, Konkel JE, Hand TW, Lacerda-Queiroz N, Su XZ, Trinchieri G, Grainger JR, Belkaid Y. Askenase MH, et al. Among authors: trinchieri g. Immunity. 2015 Jun 16;42(6):1130-42. doi: 10.1016/j.immuni.2015.05.011. Epub 2015 Jun 9. Immunity. 2015. PMID: 26070484 Free PMC article.
Microbiota-Dependent Sequelae of Acute Infection Compromise Tissue-Specific Immunity.
Fonseca DM, Hand TW, Han SJ, Gerner MY, Glatman Zaretsky A, Byrd AL, Harrison OJ, Ortiz AM, Quinones M, Trinchieri G, Brenchley JM, Brodsky IE, Germain RN, Randolph GJ, Belkaid Y. Fonseca DM, et al. Among authors: trinchieri g. Cell. 2015 Oct 8;163(2):354-66. doi: 10.1016/j.cell.2015.08.030. Cell. 2015. PMID: 26451485 Free PMC article.
On-going Mechanical Damage from Mastication Drives Homeostatic Th17 Cell Responses at the Oral Barrier.
Dutzan N, Abusleme L, Bridgeman H, Greenwell-Wild T, Zangerle-Murray T, Fife ME, Bouladoux N, Linley H, Brenchley L, Wemyss K, Calderon G, Hong BY, Break TJ, Bowdish DME, Lionakis MS, Jones SA, Trinchieri G, Diaz PI, Belkaid Y, Konkel JE, Moutsopoulos NM. Dutzan N, et al. Among authors: trinchieri g. Immunity. 2017 Jan 17;46(1):133-147. doi: 10.1016/j.immuni.2016.12.010. Epub 2017 Jan 10. Immunity. 2017. PMID: 28087239 Free PMC article.
Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair.
Linehan JL, Harrison OJ, Han SJ, Byrd AL, Vujkovic-Cvijin I, Villarino AV, Sen SK, Shaik J, Smelkinson M, Tamoutounour S, Collins N, Bouladoux N, Dzutsev A, Rosshart SP, Arbuckle JH, Wang CR, Kristie TM, Rehermann B, Trinchieri G, Brenchley JM, O'Shea JJ, Belkaid Y. Linehan JL, et al. Among authors: trinchieri g. Cell. 2018 Feb 8;172(4):784-796.e18. doi: 10.1016/j.cell.2017.12.033. Epub 2018 Jan 18. Cell. 2018. PMID: 29358051 Free PMC article.
Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells.
Bodogai M, O'Connell J, Kim K, Kim Y, Moritoh K, Chen C, Gusev F, Vaughan K, Shulzhenko N, Mattison JA, Lee-Chang C, Chen W, Carlson O, Becker KG, Gurung M, Morgun A, White J, Meade T, Perdue K, Mack M, Ferrucci L, Trinchieri G, de Cabo R, Rogaev E, Egan J, Wu J, Biragyn A. Bodogai M, et al. Among authors: trinchieri g. Sci Transl Med. 2018 Nov 14;10(467):eaat4271. doi: 10.1126/scitranslmed.aat4271. Sci Transl Med. 2018. PMID: 30429354 Free PMC article.
480 results