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Organ-specific off-target effects of Pim/ZIP kinase inhibitors suggest lack of contractile Pim kinase activity in prostate, bladder, and vascular smooth muscle.
Hu S, Trieb M, Huang R, Tamalunas A, Keller P, Götz M, Waidelich R, Stief CG, Hennenberg M. Hu S, et al. Among authors: trieb m. Naunyn Schmiedebergs Arch Pharmacol. 2024 Feb;397(2):1219-1231. doi: 10.1007/s00210-023-02664-6. Epub 2023 Sep 1. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 37658212 Free PMC article.
Inhibition of growth and contraction in human prostate stromal cells by silencing of NUAK1 and -2, and by the presumed NUAK inhibitors HTH01-015 and WZ4003.
Liu Y, Wang R, Huang R, Rutz B, Ciotkowska A, Tamalunas A, Hu S, Trieb M, Waidelich R, Strittmatter F, Stief CG, Hennenberg M. Liu Y, et al. Among authors: trieb m. Front Pharmacol. 2023 Apr 28;14:1105427. doi: 10.3389/fphar.2023.1105427. eCollection 2023. Front Pharmacol. 2023. PMID: 37188272 Free PMC article.
43 results