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Extracellular vesicles secreted by triple-negative breast cancer stem cells trigger premetastatic niche remodeling and metastatic growth in the lungs.
González-Callejo P, Gener P, Díaz-Riascos ZV, Conti S, Cámara-Sánchez P, Riera R, Mancilla S, García-Gabilondo M, Peg V, Arango D, Rosell A, Labernadie A, Trepat X, Albertazzi L, Schwartz S Jr, Seras-Franzoso J, Abasolo I. González-Callejo P, et al. Among authors: trepat x. Int J Cancer. 2023 May 15;152(10):2153-2165. doi: 10.1002/ijc.34447. Epub 2023 Feb 7. Int J Cancer. 2023. PMID: 36705298 Free article.
Curvature in Biological Systems: Its Quantification, Emergence, and Implications across the Scales.
Schamberger B, Ziege R, Anselme K, Ben Amar M, Bykowski M, Castro APG, Cipitria A, Coles RA, Dimova R, Eder M, Ehrig S, Escudero LM, Evans ME, Fernandes PR, Fratzl P, Geris L, Gierlinger N, Hannezo E, Iglič A, Kirkensgaard JJK, Kollmannsberger P, Kowalewska Ł, Kurniawan NA, Papantoniou I, Pieuchot L, Pires THV, Renner LD, Sageman-Furnas AO, Schröder-Turk GE, Sengupta A, Sharma VR, Tagua A, Tomba C, Trepat X, Waters SL, Yeo EF, Roschger A, Bidan CM, Dunlop JWC. Schamberger B, et al. Among authors: trepat x. Adv Mater. 2023 Mar;35(13):e2206110. doi: 10.1002/adma.202206110. Epub 2023 Feb 15. Adv Mater. 2023. PMID: 36461812 Free article. Review.
Membrane to cortex attachment determines different mechanical phenotypes in LGR5+ and LGR5- colorectal cancer cells.
Conti S, Venturini V, Cañellas-Socias A, Cortina C, Abenza JF, Stephan-Otto Attolini C, Middendorp Guerra E, Xu CK, Li JH, Rossetti L, Stassi G, Roca-Cusachs P, Diz-Muñoz A, Ruprecht V, Guck J, Batlle E, Labernadie A, Trepat X. Conti S, et al. Among authors: trepat x. Nat Commun. 2024 Apr 18;15(1):3363. doi: 10.1038/s41467-024-47227-2. Nat Commun. 2024. PMID: 38637494 Free PMC article.
Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeleton.
Beedle AEM, Jaganathan A, Albajar-Sigalés A, Yavitt FM, Bera K, Andreu I, Granero-Moya I, Zalvidea D, Kechagia Z, Wiche G, Trepat X, Ivaska J, Anseth KS, Shenoy VB, Roca-Cusachs P. Beedle AEM, et al. Among authors: trepat x. bioRxiv [Preprint]. 2023 Nov 11:2023.11.08.566191. doi: 10.1101/2023.11.08.566191. bioRxiv. 2023. PMID: 37986921 Free PMC article. Preprint.
The laminin-keratin link shields the nucleus from mechanical deformation and signalling.
Kechagia Z, Sáez P, Gómez-González M, Canales B, Viswanadha S, Zamarbide M, Andreu I, Koorman T, Beedle AEM, Elosegui-Artola A, Derksen PWB, Trepat X, Arroyo M, Roca-Cusachs P. Kechagia Z, et al. Among authors: trepat x. Nat Mater. 2023 Nov;22(11):1409-1420. doi: 10.1038/s41563-023-01657-3. Epub 2023 Sep 14. Nat Mater. 2023. PMID: 37709930 Free PMC article.
Mapping mechanical stress in curved epithelia of designed size and shape.
Marín-Llauradó A, Kale S, Ouzeri A, Golde T, Sunyer R, Torres-Sánchez A, Latorre E, Gómez-González M, Roca-Cusachs P, Arroyo M, Trepat X. Marín-Llauradó A, et al. Among authors: trepat x. Nat Commun. 2023 Jul 7;14(1):4014. doi: 10.1038/s41467-023-38879-7. Nat Commun. 2023. PMID: 37419987 Free PMC article.
124 results