Tremmel R - Search Results

1

Challenges and opportunities associated with rare-variant pharmacogenomics.

Zhou Y, Tremmel R, Schaeffeler E, Schwab M, Lauschke VM. Zhou Y, et al. Among authors: tremmel r. Trends Pharmacol Sci. 2022 Oct;43(10):852-865. doi: 10.1016/j.tips.2022.07.002. Epub 2022 Aug 22. Trends Pharmacol Sci. 2022. PMID: 36008164 Free article. Review.

2

Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1.

Tremmel R, Klein K, Winter S, Schaeffeler E, Zanger UM. Tremmel R, et al. Pharmacogenomics J. 2016 Nov;16(6):551-558. doi: 10.1038/tpj.2015.69. Epub 2015 Oct 27. Pharmacogenomics J. 2016. PMID: 26503817

3

Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study.

Worst BC, van Tilburg CM, Balasubramanian GP, Fiesel P, Witt R, Freitag A, Boudalil M, Previti C, Wolf S, Schmidt S, Chotewutmontri S, Bewerunge-Hudler M, Schick M, Schlesner M, Hutter B, Taylor L, Borst T, Sutter C, Bartram CR, Milde T, Pfaff E, Kulozik AE, von Stackelberg A, Meisel R, Borkhardt A, Reinhardt D, Klusmann JH, Fleischhack G, Tippelt S, Dirksen U, Jürgens H, Kramm CM, von Bueren AO, Westermann F, Fischer M, Burkhardt B, Wößmann W, Nathrath M, Bielack SS, Frühwald MC, Fulda S, Klingebiel T, Koscielniak E, Schwab M, Tremmel R, Driever PH, Schulte JH, Brors B, von Deimling A, Lichter P, Eggert A, Capper D, Pfister SM, Jones DT, Witt O. Worst BC, et al. Among authors: tremmel r. Eur J Cancer. 2016 Sep;65:91-101. doi: 10.1016/j.ejca.2016.06.009. Epub 2016 Jul 29. Eur J Cancer. 2016. PMID: 27479119

4

Polymorphic variation in TPMT is the principal determinant of TPMT phenotype: A meta-analysis of three genome-wide association studies.

Tamm R, Mägi R, Tremmel R, Winter S, Mihailov E, Smid A, Möricke A, Klein K, Schrappe M, Stanulla M, Houlston R, Weinshilboum R, Mlinarič Raščan I, Metspalu A, Milani L, Schwab M, Schaeffeler E. Tamm R, et al. Among authors: tremmel r. Clin Pharmacol Ther. 2017 May;101(5):684-695. doi: 10.1002/cpt.540. Epub 2017 Feb 1. Clin Pharmacol Ther. 2017. PMID: 27770449 Free PMC article. Review.

5

Genetic variation in human drug-related genes.

Schärfe CPI, Tremmel R, Schwab M, Kohlbacher O, Marks DS. Schärfe CPI, et al. Among authors: tremmel r. Genome Med. 2017 Dec 22;9(1):117. doi: 10.1186/s13073-017-0502-5. Genome Med. 2017. PMID: 29273096 Free PMC article.

6

Influence of NOD2 Variants on Trichuris suis ova Treatment Outcome in Crohn's Disease.

Jaeger SU, Schaeffeler E, Winter S, Tremmel R, Schölmerich J, Malek N, Stange EF, Schwab M, Wehkamp J. Jaeger SU, et al. Among authors: tremmel r. Front Pharmacol. 2018 Jul 16;9:764. doi: 10.3389/fphar.2018.00764. eCollection 2018. Front Pharmacol. 2018. PMID: 30061834 Free PMC article.

7

Identification of Cardiomyopathy-Associated Circulating miRNA Biomarkers in Muscular Dystrophy Female Carriers Using a Complementary Cardiac Imaging and Plasma Profiling Approach.

Florian A, Patrascu A, Tremmel R, Rösch S, Sechtem U, Schwab M, Schaeffeler E, Yilmaz A. Florian A, et al. Among authors: tremmel r. Front Physiol. 2018 Dec 21;9:1770. doi: 10.3389/fphys.2018.01770. eCollection 2018. Front Physiol. 2018. PMID: 30622476 Free PMC article.

8

A New Panel-Based Next-Generation Sequencing Method for ADME Genes Reveals Novel Associations of Common and Rare Variants With Expression in a Human Liver Cohort.

Klein K, Tremmel R, Winter S, Fehr S, Battke F, Scheurenbrand T, Schaeffeler E, Biskup S, Schwab M, Zanger UM. Klein K, et al. Among authors: tremmel r. Front Genet. 2019 Jan 31;10:7. doi: 10.3389/fgene.2019.00007. eCollection 2019. Front Genet. 2019. PMID: 30766545 Free PMC article.

9

The Impact of CYP3A4*22 on Tacrolimus Pharmacokinetics and Outcome in Clinical Practice at a Single Kidney Transplant Center.

Abdel-Kahaar E, Winter S, Tremmel R, Schaeffeler E, Olbricht CJ, Wieland E, Schwab M, Shipkova M, Jaeger SU. Abdel-Kahaar E, et al. Among authors: tremmel r. Front Genet. 2019 Sep 26;10:871. doi: 10.3389/fgene.2019.00871. eCollection 2019. Front Genet. 2019. PMID: 31616470 Free PMC article.

10

Copy number variation profiling in pharmacogenes using panel-based exome resequencing and correlation to human liver expression.

Tremmel R, Klein K, Battke F, Fehr S, Winter S, Scheurenbrand T, Schaeffeler E, Biskup S, Schwab M, Zanger UM. Tremmel R, et al. Hum Genet. 2020 Feb;139(2):137-149. doi: 10.1007/s00439-019-02093-7. Epub 2019 Nov 30. Hum Genet. 2020. PMID: 31786673

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