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Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function.
Lercher A, Bhattacharya A, Popa AM, Caldera M, Schlapansky MF, Baazim H, Agerer B, Gürtl B, Kosack L, Májek P, Brunner JS, Vitko D, Pinter T, Genger JW, Orlova A, Pikor N, Reil D, Ozsvár-Kozma M, Kalinke U, Ludewig B, Moriggl R, Bennett KL, Menche J, Cheng PN, Schabbauer G, Trauner M, Klavins K, Bergthaler A. Lercher A, et al. Among authors: trauner m. Immunity. 2019 Dec 17;51(6):1074-1087.e9. doi: 10.1016/j.immuni.2019.10.014. Epub 2019 Nov 26. Immunity. 2019. PMID: 31784108 Free PMC article.
Disruption of the growth hormone--signal transducer and activator of transcription 5--insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis.
Blaas L, Kornfeld JW, Schramek D, Musteanu M, Zollner G, Gumhold J, van Zijl F, Schneller D, Esterbauer H, Egger G, Mair M, Kenner L, Mikulits W, Eferl R, Moriggl R, Penninger J, Trauner M, Casanova E. Blaas L, et al. Among authors: trauner m. Hepatology. 2010 Apr;51(4):1319-26. doi: 10.1002/hep.23469. Hepatology. 2010. PMID: 20162728 Free PMC article.
24-Norursodeoxycholic acid reshapes immunometabolism in CD8+ T cells and alleviates hepatic inflammation.
Zhu C, Boucheron N, Müller AC, Májek P, Claudel T, Halilbasic E, Baazim H, Lercher A, Viczenczova C, Hainberger D, Preglej T, Sandner L, Alteneder M, Gülich AF, Khan M, Hamminger P, Remetic J, Ohradanova-Repic A, Schatzlmaier P, Donner C, Fuchs CD, Stojakovic T, Scharnagl H, Sakaguchi S, Weichhart T, Bergthaler A, Stockinger H, Ellmeier W, Trauner M. Zhu C, et al. Among authors: trauner m. J Hepatol. 2021 Nov;75(5):1164-1176. doi: 10.1016/j.jhep.2021.06.036. Epub 2021 Jul 7. J Hepatol. 2021. PMID: 34242699 Free PMC article.
A prospective evaluation of pulmonary, systemic and hepatic haemodynamics in HIV-HCV-coinfected patients before and after antiviral therapy with pegylated interferon and ribavirin.
Reiberger T, Payer BA, Ferlitsch A, Sieghart W, Breitenecker F, Aichelburg MC, Schmied B, Rieger A, Trauner M, Peck-Radosavljevic M; Vienna Hepatic Hemodynamic Lab and Vienna HIV & Liver Study Group. Reiberger T, et al. Among authors: trauner m. Antivir Ther. 2012;17(7):1327-34. doi: 10.3851/IMP2349. Epub 2012 Sep 5. Antivir Ther. 2012. PMID: 22948263
The Tyrosine Kinase Tec Regulates Effector Th17 Differentiation, Pathogenicity, and Plasticity in T-Cell-Driven Intestinal Inflammation.
Sandner L, Alteneder M, Zhu C, Hladik A, Högler S, Rica R, Van Greuningen LW, Sharif O, Sakaguchi S, Knapp S, Kenner L, Trauner M, Ellmeier W, Boucheron N. Sandner L, et al. Among authors: trauner m. Front Immunol. 2021 Dec 21;12:750466. doi: 10.3389/fimmu.2021.750466. eCollection 2021. Front Immunol. 2021. PMID: 35003062 Free PMC article.
Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
Moustafa T, Fickert P, Magnes C, Guelly C, Thueringer A, Frank S, Kratky D, Sattler W, Reicher H, Sinner F, Gumhold J, Silbert D, Fauler G, Höfler G, Lass A, Zechner R, Trauner M. Moustafa T, et al. Among authors: trauner m. Gastroenterology. 2012 Jan;142(1):140-151.e12. doi: 10.1053/j.gastro.2011.09.051. Epub 2011 Oct 14. Gastroenterology. 2012. PMID: 22001865
The interaction of hepatic lipid and glucose metabolism in liver diseases.
Bechmann LP, Hannivoort RA, Gerken G, Hotamisligil GS, Trauner M, Canbay A. Bechmann LP, et al. Among authors: trauner m. J Hepatol. 2012 Apr;56(4):952-64. doi: 10.1016/j.jhep.2011.08.025. Epub 2011 Dec 13. J Hepatol. 2012. PMID: 22173168 Free article. Review.
777 results