Trauelsen M - Search Results

1

GLP-1-directed NMDA receptor antagonism for obesity treatment.

Petersen J, Ludwig MQ, Juozaityte V, Ranea-Robles P, Svendsen C, Hwang E, Kristensen AW, Fadahunsi N, Lund J, Breum AW, Mathiesen CV, Sachs L, Moreno-Justicia R, Rohlfs R, Ford JC, Douros JD, Finan B, Portillo B, Grose K, Petersen JE, Trauelsen M, Feuchtinger A, DiMarchi RD, Schwartz TW, Deshmukh AS, Thomsen MB, Kohlmeier KA, Williams KW, Pers TH, Frølund B, Strømgaard K, Klein AB, Clemmensen C. Petersen J, et al. Among authors: trauelsen m. Nature. 2024 May 15. doi: 10.1038/s41586-024-07419-8. Online ahead of print. Nature. 2024. PMID: 38750368

2

Molecular dynamics-based identification of binding pathways and two distinct high-affinity sites for succinate in succinate receptor 1/GPR91.

Shenol A, Lückmann M, Trauelsen M, Lambrughi M, Tiberti M, Papaleo E, Frimurer TM, Schwartz TW. Shenol A, et al. Among authors: trauelsen m. Mol Cell. 2024 Mar 7;84(5):955-966.e4. doi: 10.1016/j.molcel.2024.01.011. Epub 2024 Feb 6. Mol Cell. 2024. PMID: 38325379 Free article.

3

Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4.

Lundø K, Dmytriyeva O, Spøhr L, Goncalves-Alves E, Yao J, Blasco LP, Trauelsen M, Ponniah M, Severin M, Sandelin A, Kveiborg M, Schwartz TW, Pedersen SF. Lundø K, et al. Among authors: trauelsen m. BMC Cancer. 2023 Nov 22;23(1):1136. doi: 10.1186/s12885-023-11631-6. BMC Cancer. 2023. PMID: 37993804 Free PMC article.

4

G-Protein-Coupled Receptor 91-Dependent Signalling Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidaemic Mice.

Griepke S, Trauelsen M, Nilsson MD, Hansen J, Steffensen LB, Schwartz TW, Ketelhuth DFJ. Griepke S, et al. Among authors: trauelsen m. Cells. 2023 Nov 6;12(21):2580. doi: 10.3390/cells12212580. Cells. 2023. PMID: 37947659 Free PMC article.

5

Free fatty acid receptor 1 stimulates cAMP production and gut hormone secretion through Gq-mediated activation of adenylate cyclase 2.

Petersen JE, Pedersen MH, Dmytriyeva O, Nellemose E, Arora T, Engelstoft MS, Asher WB, Javitch JA, Schwartz TW, Trauelsen M. Petersen JE, et al. Among authors: trauelsen m. Mol Metab. 2023 Aug;74:101757. doi: 10.1016/j.molmet.2023.101757. Epub 2023 Jun 20. Mol Metab. 2023. PMID: 37348738 Free PMC article.

6

Pyruvate dehydrogenase kinase regulates vascular inflammation in atherosclerosis and increases cardiovascular risk.

Forteza MJ, Berg M, Edsfeldt A, Sun J, Baumgartner R, Kareinen I, Casagrande FB, Hedin U, Zhang S, Vuckovic I, Dzeja PP, Polyzos KA, Gisterå A, Trauelsen M, Schwartz TW, Dib L, Herrmann J, Monaco C, Matic L, Gonçalves I, Ketelhuth DFJ. Forteza MJ, et al. Among authors: trauelsen m. Cardiovasc Res. 2023 Jul 4;119(7):1524-1536. doi: 10.1093/cvr/cvad038. Cardiovasc Res. 2023. PMID: 36866436 Free PMC article.

7

Cell selectivity in succinate receptor SUCNR1/GPR91 signaling in skeletal muscle.

Abdelmoez AM, Dmytriyeva O, Zurke YX, Trauelsen M, Marica AA, Savikj M, Smith JAB, Monaco C, Schwartz TW, Krook A, Pillon NJ. Abdelmoez AM, et al. Among authors: trauelsen m. Am J Physiol Endocrinol Metab. 2023 Apr 1;324(4):E289-E298. doi: 10.1152/ajpendo.00009.2023. Epub 2023 Feb 22. Am J Physiol Endocrinol Metab. 2023. PMID: 36812387 Free article.

8

Activation of succinate receptor 1 boosts human mast cell reactivity and allergic bronchoconstriction.

Tang X, Rönnberg E, Säfholm J, Thulasingam M, Trauelsen M, Schwartz TW, Wheelock CE, Dahlén SE, Nilsson G, Haeggström JZ. Tang X, et al. Among authors: trauelsen m. Allergy. 2022 Sep;77(9):2677-2687. doi: 10.1111/all.15245. Epub 2022 Feb 14. Allergy. 2022. PMID: 35122266 Free PMC article.

9

Protective succinate-SUCNR1 metabolic stress signaling gone bad.

Winther S, Trauelsen M, Schwartz TW. Winther S, et al. Among authors: trauelsen m. Cell Metab. 2021 Jul 6;33(7):1276-1278. doi: 10.1016/j.cmet.2021.06.009. Cell Metab. 2021. PMID: 34233171 Free article.

10

Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling.

Trauelsen M, Hiron TK, Lin D, Petersen JE, Breton B, Husted AS, Hjorth SA, Inoue A, Frimurer TM, Bouvier M, O'Callaghan CA, Schwartz TW. Trauelsen M, et al. Cell Rep. 2021 Jun 15;35(11):109246. doi: 10.1016/j.celrep.2021.109246. Cell Rep. 2021. PMID: 34133934 Free article.

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