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Polygenic risk for schizophrenia converges on alternative polyadenylation as molecular mechanism underlying synaptic impairment.
Raabe FJ, Hausruckinger A, Gagliardi M, Ahmad R, Almeida V, Galinski S, Hoffmann A, Weigert L, Rummel CK, Murek V, Trastulla L, Jimenez-Barron L, Atella A, Maidl S, Menegaz D, Hauger B, Wagner EM, Gabellini N, Kauschat B, Riccardo S, Cesana M, Papiol S, Sportelli V, Rex-Haffner M, Stolte SJ, Wehr MC, Salcedo TO, Papazova I, Detera-Wadleigh S, McMahon FJ, Schmitt A, Falkai P, Hasan A, Cacchiarelli D, Dannlowski U, Nenadić I, Kircher T, Scheuss V, Eder M, Binder EB, Spengler D, Rossner MJ, Ziller MJ. Raabe FJ, et al. Among authors: trastulla l. bioRxiv [Preprint]. 2024 Jan 13:2024.01.09.574815. doi: 10.1101/2024.01.09.574815. bioRxiv. 2024. PMID: 38260577 Free PMC article. Preprint.
Massively parallel functional dissection of schizophrenia-associated noncoding genetic variants.
Rummel CK, Gagliardi M, Ahmad R, Herholt A, Jimenez-Barron L, Murek V, Weigert L, Hausruckinger A, Maidl S, Hauger B, Raabe FJ, Fürle C, Trastulla L, Turecki G, Eder M, Rossner MJ, Ziller MJ. Rummel CK, et al. Among authors: trastulla l. Cell. 2023 Nov 9;186(23):5165-5182.e33. doi: 10.1016/j.cell.2023.09.015. Epub 2023 Oct 17. Cell. 2023. PMID: 37852259
Highlights from the 1st European cancer dependency map symposium and workshop.
Trastulla L, Savino A, Beltrao P, Ciriano IC, Fenici P, Garnett MJ, Guerini I, Bigas NL, Mattaj I, Petsalaki E, Riva L, Tape CJ, Leeuwen JV, Sharma S, Vazquez F, Iorio F. Trastulla L, et al. FEBS Lett. 2023 Aug;597(15):1921-1927. doi: 10.1002/1873-3468.14699. Epub 2023 Jul 24. FEBS Lett. 2023. PMID: 37487655
Distinct genetic liability profiles define clinically relevant patient strata across common diseases.
Trastulla L, Moser S, Jiménez-Barrón LT, Andlauer TFM, von Scheidt M; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Budde M, Heilbronner U, Papiol S, Teumer A, Homuth G, Falkai P, Völzke H, Dörr M, Schulze TG, Gagneur J, Iorio F, Müller-Myhsok B, Schunkert H, Ziller MJ. Trastulla L, et al. medRxiv [Preprint]. 2023 May 11:2023.05.10.23289788. doi: 10.1101/2023.05.10.23289788. medRxiv. 2023. PMID: 37214898 Free PMC article. Preprint.
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