Toyooka N - Search Results

1

A New Method for Albuminuria Measurement Using a Specific Reaction between Albumin and the Luciferin of the Firefly Squid Watasenia scintillans.

Ishimoto T, Okada T, Fujisaka S, Yagi K, Tobe K, Toyooka N, Mori H. Ishimoto T, et al. Among authors: toyooka n. Int J Mol Sci. 2022 Jul 28;23(15):8342. doi: 10.3390/ijms23158342. Int J Mol Sci. 2022. PMID: 35955470 Free PMC article.

2

In silico and pharmacological screenings identify novel serine racemase inhibitors.

Mori H, Wada R, Li J, Ishimoto T, Mizuguchi M, Obita T, Gouda H, Hirono S, Toyooka N. Mori H, et al. Among authors: toyooka n. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3732-5. doi: 10.1016/j.bmcl.2014.07.003. Epub 2014 Jul 5. Bioorg Med Chem Lett. 2014. PMID: 25066953

3

Discovery of novel adenylyl cyclase inhibitor by cell-based screening.

Mano H, Ishimoto T, Okada T, Toyooka N, Mori H. Mano H, et al. Among authors: toyooka n. Biol Pharm Bull. 2014;37(10):1689-93. doi: 10.1248/bpb.b14-00283. Biol Pharm Bull. 2014. PMID: 25273392 Free article.

4

Synthesis of new tricyclic thiolactams as potent antitumor agent for pancreatic cancer.

Okada T, Minehira D, Takada M, Urata H, Kato A, Adachi I, Kurashima Y, Kaji S, Ogura T, Chiba S, Esumi H, Toyooka N. Okada T, et al. Among authors: toyooka n. Bioorg Med Chem Lett. 2016 Jun 1;26(11):2577-9. doi: 10.1016/j.bmcl.2016.04.035. Epub 2016 Apr 16. Bioorg Med Chem Lett. 2016. PMID: 27117432

5

A novel serine racemase inhibitor suppresses neuronal over-activation in vivo.

Mori H, Wada R, Takahara S, Horino Y, Izumi H, Ishimoto T, Yoshida T, Mizuguchi M, Obita T, Gouda H, Hirono S, Toyooka N. Mori H, et al. Among authors: toyooka n. Bioorg Med Chem. 2017 Jul 15;25(14):3736-3745. doi: 10.1016/j.bmc.2017.05.011. Epub 2017 May 11. Bioorg Med Chem. 2017. PMID: 28533113

6

Design, synthesis, and evaluation of novel inhibitors for wild-type human serine racemase.

Takahara S, Nakagawa K, Uchiyama T, Yoshida T, Matsumoto K, Kawasumi Y, Mizuguchi M, Obita T, Watanabe Y, Hayakawa D, Gouda H, Mori H, Toyooka N. Takahara S, et al. Among authors: toyooka n. Bioorg Med Chem Lett. 2018 Feb 1;28(3):441-445. doi: 10.1016/j.bmcl.2017.12.021. Epub 2017 Dec 13. Bioorg Med Chem Lett. 2018. PMID: 29277459

7

Design and synthesis of novel anti-hyperalgesic agents based on 6-prenylnaringenin as the T-type calcium channel blockers.

Du Nguyen H, Okada T, Kitamura S, Yamaoka S, Horaguchi Y, Kasanami Y, Sekiguchi F, Tsubota M, Yoshida S, Nishikawa H, Kawabata A, Toyooka N. Du Nguyen H, et al. Among authors: toyooka n. Bioorg Med Chem. 2018 Aug 15;26(15):4410-4427. doi: 10.1016/j.bmc.2018.07.023. Epub 2018 Jul 19. Bioorg Med Chem. 2018. PMID: 30031654

8

The novel small-molecule antagonist of PAC1 receptor attenuates formalin-induced inflammatory pain behaviors in mice.

Takasaki I, Nakamura K, Shimodaira A, Watanabe A, Du Nguyen H, Okada T, Toyooka N, Miyata A, Kurihara T. Takasaki I, et al. Among authors: toyooka n. J Pharmacol Sci. 2019 Feb;139(2):129-132. doi: 10.1016/j.jphs.2018.11.011. Epub 2018 Dec 1. J Pharmacol Sci. 2019. PMID: 30552012 Free article.

9

Critical role of Ca_v3.2 T-type calcium channels in the peripheral neuropathy induced by bortezomib, a proteasome-inhibiting chemotherapeutic agent, in mice.

Tomita S, Sekiguchi F, Deguchi T, Miyazaki T, Ikeda Y, Tsubota M, Yoshida S, Nguyen HD, Okada T, Toyooka N, Kawabata A. Tomita S, et al. Among authors: toyooka n. Toxicology. 2019 Feb 1;413:33-39. doi: 10.1016/j.tox.2018.12.003. Epub 2018 Dec 12. Toxicology. 2019. PMID: 30552955

10

Design and synthesis of functionalized coumarins as potential anti-austerity agents that eliminates cancer cells' tolerance to nutrition starvation.

Awale S, Okada T, Dibwe DF, Maruyama T, Takahara S, Okada T, Endo S, Toyooka N. Awale S, et al. Among authors: toyooka n. Bioorg Med Chem Lett. 2019 Jul 15;29(14):1779-1784. doi: 10.1016/j.bmcl.2019.05.010. Epub 2019 May 8. Bioorg Med Chem Lett. 2019. PMID: 31097375

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