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Circular RNAs drive oncogenic chromosomal translocations within the MLL recombinome in leukemia.
Conn VM, Gabryelska M, Toubia J, Kirk K, Gantley L, Powell JA, Cildir G, Marri S, Liu R, Stringer BW, Townley S, Webb ST, Lin H, Samaraweera SE, Bailey S, Moore AS, Maybury M, Liu D, Colella AD, Chataway T, Wallington-Gates CT, Walters L, Sibbons J, Selth LA, Tergaonkar V, D'Andrea RJ, Pitson SM, Goodall GJ, Conn SJ. Conn VM, et al. Among authors: toubia j. Cancer Cell. 2023 Jul 10;41(7):1309-1326.e10. doi: 10.1016/j.ccell.2023.05.002. Epub 2023 Jun 8. Cancer Cell. 2023. PMID: 37295428
The RNA binding protein quaking regulates formation of circRNAs.
Conn SJ, Pillman KA, Toubia J, Conn VM, Salmanidis M, Phillips CA, Roslan S, Schreiber AW, Gregory PA, Goodall GJ. Conn SJ, et al. Among authors: toubia j. Cell. 2015 Mar 12;160(6):1125-34. doi: 10.1016/j.cell.2015.02.014. Cell. 2015. PMID: 25768908 Free article.
Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia.
Powell JA, Lewis AC, Zhu W, Toubia J, Pitman MR, Wallington-Beddoe CT, Moretti PA, Iarossi D, Samaraweera SE, Cummings N, Ramshaw HS, Thomas D, Wei AH, Lopez AF, D'Andrea RJ, Lewis ID, Pitson SM. Powell JA, et al. Among authors: toubia j. Blood. 2017 Feb 9;129(6):771-782. doi: 10.1182/blood-2016-06-720433. Epub 2016 Dec 12. Blood. 2017. PMID: 27956387 Free PMC article.
Naturally existing isoforms of miR-222 have distinct functions.
Yu F, Pillman KA, Neilsen CT, Toubia J, Lawrence DM, Tsykin A, Gantier MP, Callen DF, Goodall GJ, Bracken CP. Yu F, et al. Among authors: toubia j. Nucleic Acids Res. 2017 Nov 2;45(19):11371-11385. doi: 10.1093/nar/gkx788. Nucleic Acids Res. 2017. PMID: 28981911 Free PMC article.
miR-200/375 control epithelial plasticity-associated alternative splicing by repressing the RNA-binding protein Quaking.
Pillman KA, Phillips CA, Roslan S, Toubia J, Dredge BK, Bert AG, Lumb R, Neumann DP, Li X, Conn SJ, Liu D, Bracken CP, Lawrence DM, Stylianou N, Schreiber AW, Tilley WD, Hollier BG, Khew-Goodall Y, Selth LA, Goodall GJ, Gregory PA. Pillman KA, et al. Among authors: toubia j. EMBO J. 2018 Jul 2;37(13):e99016. doi: 10.15252/embj.201899016. Epub 2018 Jun 5. EMBO J. 2018. PMID: 29871889 Free PMC article.
Extensive transcriptional responses are co-ordinated by microRNAs as revealed by Exon-Intron Split Analysis (EISA).
Pillman KA, Scheer KG, Hackett-Jones E, Saunders K, Bert AG, Toubia J, Whitfield HJ, Sapkota S, Sourdin L, Pham H, Le TD, Cursons J, Davis MJ, Gregory PA, Goodall GJ, Bracken CP. Pillman KA, et al. Among authors: toubia j. Nucleic Acids Res. 2019 Sep 19;47(16):8606-8619. doi: 10.1093/nar/gkz664. Nucleic Acids Res. 2019. PMID: 31372646 Free PMC article.
42 results