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Probing small molecule binding to amyloid fibrils.
Buell AK, Esbjörner EK, Riss PJ, White DA, Aigbirhio FI, Toth G, Welland ME, Dobson CM, Knowles TP. Buell AK, et al. Among authors: toth g. Phys Chem Chem Phys. 2011 Dec 7;13(45):20044-52. doi: 10.1039/c1cp22283j. Epub 2011 Oct 17. Phys Chem Chem Phys. 2011. PMID: 22006124 Review.
Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease.
Tóth G, Gardai SJ, Zago W, Bertoncini CW, Cremades N, Roy SL, Tambe MA, Rochet JC, Galvagnion C, Skibinski G, Finkbeiner S, Bova M, Regnstrom K, Chiou SS, Johnston J, Callaway K, Anderson JP, Jobling MF, Buell AK, Yednock TA, Knowles TP, Vendruscolo M, Christodoulou J, Dobson CM, Schenk D, McConlogue L. Tóth G, et al. PLoS One. 2014 Feb 14;9(2):e87133. doi: 10.1371/journal.pone.0087133. eCollection 2014. PLoS One. 2014. PMID: 24551051 Free PMC article.
Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies.
Pickhardt M, Neumann T, Schwizer D, Callaway K, Vendruscolo M, Schenk D, St George-Hyslop P, Mandelkow EM, Dobson CM, McConlogue L, Mandelkow E, Tóth G. Pickhardt M, et al. Among authors: toth g. Curr Alzheimer Res. 2015;12(9):814-28. doi: 10.2174/156720501209151019104951. Curr Alzheimer Res. 2015. PMID: 26510979 Free PMC article.
DJ-1 can form β-sheet structured aggregates that co-localize with pathological amyloid deposits.
Solti K, Kuan WL, Fórizs B, Kustos G, Mihály J, Varga Z, Herberth B, Moravcsik É, Kiss R, Kárpáti M, Mikes A, Zhao Y, Imre T, Rochet JC, Aigbirhio F, Williams-Gray CH, Barker RA, Tóth G. Solti K, et al. Among authors: toth g. Neurobiol Dis. 2020 Feb;134:104629. doi: 10.1016/j.nbd.2019.104629. Epub 2019 Nov 11. Neurobiol Dis. 2020. PMID: 31669752 Free article.
Corrigendum to "DJ-1 can form β-sheet structured aggregates that co-localize with pathological amyloid deposits". Neurobiology of Disease 134 (2020) 104629.
Solti K, Kuan WL, Fórizs B, Kustos G, Mihály J, Varga Z, Herberth B, Moravcsik É, Kiss R, Kárpáti M, Mikes A, Zhao Y, Imre T, Rochet JC, Aigbirhio F, Williams-Gray CH, Barker RA, Tóth G. Solti K, et al. Among authors: toth g. Neurobiol Dis. 2020 Aug;142:104971. doi: 10.1016/j.nbd.2020.104971. Epub 2020 Jun 20. Neurobiol Dis. 2020. PMID: 32576487 Free article. No abstract available.
1,414 results