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Nilotinib Effects on Safety, Tolerability, and Biomarkers in Alzheimer's Disease.
Turner RS, Hebron ML, Lawler A, Mundel EE, Yusuf N, Starr JN, Anjum M, Pagan F, Torres-Yaghi Y, Shi W, Mulki S, Ferrante D, Matar S, Liu X, Esposito G, Berkowitz F, Jiang X, Ahn J, Moussa C. Turner RS, et al. Ann Neurol. 2020 Jul;88(1):183-194. doi: 10.1002/ana.25775. Epub 2020 May 28. Ann Neurol. 2020. PMID: 32468646 Free PMC article.
Nilotinib Effects in Parkinson's disease and Dementia with Lewy bodies.
Pagan F, Hebron M, Valadez EH, Torres-Yaghi Y, Huang X, Mills RR, Wilmarth BM, Howard H, Dunn C, Carlson A, Lawler A, Rogers SL, Falconer RA, Ahn J, Li Z, Moussa C. Pagan F, et al. J Parkinsons Dis. 2016 Jul 11;6(3):503-17. doi: 10.3233/JPD-160867. J Parkinsons Dis. 2016. PMID: 27434297 Free PMC article. Clinical Trial.
Lewy Body Dementia Association's Research Centers of Excellence Program: Inaugural Meeting Proceedings.
Peterson B, Armstrong M, Galasko D, Galvin JE, Goldman J, Irwin D, Paulson H, Kaufer D, Leverenz J, Lunde A, McKeith IG, Siderowf A, Taylor A, Amodeo K, Barrett M, Domoto-Reilly K, Duda J, Gomperts S, Graff-Radford N, Holden S, Honig L, Huddleston D, Lippa C, Litvan I, Manning C, Marder K, Moussa C, Onyike C, Pagan F, Pantelyat A, Pelak V, Poston K, Quinn J, Richard I, Rosenthal LS, Sabbagh M, Scharre D, Sha S, Shill H, Torres-Yaghi Y, Christie T, Graham T, Richards I, Koehler M, Boeve B. Peterson B, et al. Alzheimers Res Ther. 2019 Mar 13;11(1):23. doi: 10.1186/s13195-019-0476-1. Alzheimers Res Ther. 2019. PMID: 30867052 Free PMC article. Review.
Pharmacokinetics and pharmacodynamics of a single dose Nilotinib in individuals with Parkinson's disease.
Pagan FL, Hebron ML, Wilmarth B, Torres-Yaghi Y, Lawler A, Mundel EE, Yusuf N, Starr NJ, Arellano J, Howard HH, Peyton M, Matar S, Liu X, Fowler AJ, Schwartz SL, Ahn J, Moussa C. Pagan FL, et al. Pharmacol Res Perspect. 2019 Mar 12;7(2):e00470. doi: 10.1002/prp2.470. eCollection 2019 Apr. Pharmacol Res Perspect. 2019. PMID: 30906562 Free PMC article. Clinical Trial.
Nilotinib Effects on Safety, Tolerability, and Potential Biomarkers in Parkinson Disease: A Phase 2 Randomized Clinical Trial.
Pagan FL, Hebron ML, Wilmarth B, Torres-Yaghi Y, Lawler A, Mundel EE, Yusuf N, Starr NJ, Anjum M, Arellano J, Howard HH, Shi W, Mulki S, Kurd-Misto T, Matar S, Liu X, Ahn J, Moussa C. Pagan FL, et al. JAMA Neurol. 2020 Mar 1;77(3):309-317. doi: 10.1001/jamaneurol.2019.4200. JAMA Neurol. 2020. PMID: 31841599 Free PMC article. Clinical Trial.
Discoidin Domain Receptor 1 is a therapeutic target for neurodegenerative diseases.
Fowler AJ, Hebron M, Balaraman K, Shi W, Missner AA, Greenzaid JD, Chiu TL, Ullman C, Weatherdon E, Duka V, Torres-Yaghi Y, Pagan FL, Liu X, Ressom H, Ahn J, Wolf C, Moussa C. Fowler AJ, et al. Hum Mol Genet. 2020 Oct 10;29(17):2882-2898. doi: 10.1093/hmg/ddaa177. Hum Mol Genet. 2020. PMID: 32776088 Free PMC article.
Sialorrhea in Parkinson's Disease.
Isaacson J, Patel S, Torres-Yaghi Y, Pagán F. Isaacson J, et al. Toxins (Basel). 2020 Oct 31;12(11):691. doi: 10.3390/toxins12110691. Toxins (Basel). 2020. PMID: 33142833 Free PMC article. Review.
25 results