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p53 wild-type colorectal cancer cells that express a fetal gene signature are associated with metastasis and poor prognosis.
Solé L, Lobo-Jarne T, Álvarez-Villanueva D, Alonso-Marañón J, Guillén Y, Guix M, Sangrador I, Rozalén C, Vert A, Barbachano A, Lop J, Salido M, Bellosillo B, García-Romero R, Garrido M, González J, Martínez-Iniesta M, López-Arribillaga E, Salazar R, Montagut C, Torres F, Iglesias M, Celià-Terrassa T, Muñoz A, Villanueva A, Bigas A, Espinosa L. Solé L, et al. Among authors: torres f. Nat Commun. 2022 May 23;13(1):2866. doi: 10.1038/s41467-022-30382-9. Nat Commun. 2022. PMID: 35606354 Free PMC article.
Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer.
Rodilla V, Villanueva A, Obrador-Hevia A, Robert-Moreno A, Fernández-Majada V, Grilli A, López-Bigas N, Bellora N, Albà MM, Torres F, Duñach M, Sanjuan X, Gonzalez S, Gridley T, Capella G, Bigas A, Espinosa L. Rodilla V, et al. Among authors: torres f. Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6315-20. doi: 10.1073/pnas.0813221106. Epub 2009 Mar 26. Proc Natl Acad Sci U S A. 2009. PMID: 19325125 Free PMC article.
A truncated form of IKKα is responsible for specific nuclear IKK activity in colorectal cancer.
Margalef P, Fernández-Majada V, Villanueva A, Garcia-Carbonell R, Iglesias M, López L, Martínez-Iniesta M, Villà-Freixa J, Mulero MC, Andreu M, Torres F, Mayo MW, Bigas A, Espinosa L. Margalef P, et al. Among authors: torres f. Cell Rep. 2012 Oct 25;2(4):840-54. doi: 10.1016/j.celrep.2012.08.028. Epub 2012 Oct 4. Cell Rep. 2012. PMID: 23041317 Free article.
Novel phosphorylated TAK1 species with functional impact on NF-κB and β-catenin signaling in human Cutaneous T-cell lymphoma.
Gallardo F, Bertran J, López-Arribillaga E, González J, Menéndez S, Sánchez I, Colomo L, Iglesias M, Garrido M, Santamaría-Babí LF, Torres F, Pujol RM, Bigas A, Espinosa L. Gallardo F, et al. Among authors: torres f. Leukemia. 2018 Oct;32(10):2211-2223. doi: 10.1038/s41375-018-0066-4. Epub 2018 Feb 22. Leukemia. 2018. PMID: 29511289 Free PMC article.
Manic Fringe deficiency imposes Jagged1 addiction to intestinal tumor cells.
López-Arribillaga E, Rodilla V, Colomer C, Vert A, Shelton A, Cheng JH, Yan B, Gonzalez-Perez A, Junttila MR, Iglesias M, Torres F, Albanell J, Villanueva A, Bigas A, Siebel CW, Espinosa L. López-Arribillaga E, et al. Among authors: torres f. Nat Commun. 2018 Jul 31;9(1):2992. doi: 10.1038/s41467-018-05385-0. Nat Commun. 2018. PMID: 30065304 Free PMC article.
Design and endpoints of clinical and translational trials in advanced colorectal cancer. a proposal from GROUP Español Multidisciplinar en Cancer Digestivo (GEMCAD).
Carrera G, Garcia-Albeniz X, Ayuso JR, Aparicio J, Castells A, Codony-Servat J, Feliu J, Fuster D, Gallego R, Pagés M, Torres F, Maurel J. Carrera G, et al. Among authors: torres f. Rev Recent Clin Trials. 2011 May;6(2):158-70. doi: 10.2174/157488711795177868. Rev Recent Clin Trials. 2011. PMID: 21241233 Review.
A Phase I-II multicenter trial with Avelumab plus autologous dendritic cell vaccine in pre-treated mismatch repair-proficient (MSS) metastatic colorectal cancer patients; GEMCAD 1602 study.
Español-Rego M, Fernández-Martos C, Elez E, Foguet C, Pedrosa L, Rodríguez N, Ruiz-Casado A, Pineda E, Cid J, Cabezón R, Oliveres H, Lozano M, Ginés A, García-Criado A, Ayuso JR, Pagés M, Cuatrecasas M, Torres F, Thomson T, Cascante M, Benítez-Ribas D, Maurel J. Español-Rego M, et al. Among authors: torres f. Cancer Immunol Immunother. 2023 Apr;72(4):827-840. doi: 10.1007/s00262-022-03283-5. Epub 2022 Sep 9. Cancer Immunol Immunother. 2023. PMID: 36083313 Free PMC article.
Early diarrhoea under sorafenib as a marker to consider the early migration to second-line drugs.
Díaz-González Á, Sapena V, Boix L, Torres F, Sanduzzi-Zamparelli M, Da Fonseca LG, LLarch N, Iserte G, Guedes C, Muñoz-Martínez S, Darnell A, Belmonte E, Rimola J, Forner A, Ayuso C, Bruix J, Reig M. Díaz-González Á, et al. Among authors: torres f. United European Gastroenterol J. 2021 Jul;9(6):655-661. doi: 10.1002/ueg2.12111. Epub 2021 Jul 6. United European Gastroenterol J. 2021. PMID: 34228394 Free PMC article.
1,301 results