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Novel Heteroaryl Selenocyanates and Diselenides as Potent Antileishmanial Agents.
Baquedano Y, Alcolea V, Toro MÁ, Gutiérrez KJ, Nguewa P, Font M, Moreno E, Espuelas S, Jiménez-Ruiz A, Palop JA, Plano D, Sanmartín C. Baquedano Y, et al. Among authors: toro ma. Antimicrob Agents Chemother. 2016 May 23;60(6):3802-12. doi: 10.1128/AAC.02529-15. Print 2016 Jun. Antimicrob Agents Chemother. 2016. PMID: 27067328 Free PMC article.
Synthesis and Leishmanicidal Activity of Novel Urea, Thiourea, and Selenourea Derivatives of Diselenides.
Díaz M, de Lucio H, Moreno E, Espuelas S, Aydillo C, Jiménez-Ruiz A, Toro MÁ, Gutiérrez KJ, Martínez-Merino V, Cornejo A, Palop JA, Sanmartín C, Plano D. Díaz M, et al. Among authors: toro ma. Antimicrob Agents Chemother. 2019 Apr 25;63(5):e02200-18. doi: 10.1128/AAC.02200-18. Print 2019 May. Antimicrob Agents Chemother. 2019. PMID: 30782984 Free PMC article.
First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity.
Ruiz-Santaquiteria M, Sánchez-Murcia PA, Toro MA, de Lucio H, Gutiérrez KJ, de Castro S, Carneiro FAC, Gago F, Jiménez-Ruiz A, Camarasa MJ, Velázquez S. Ruiz-Santaquiteria M, et al. Among authors: toro ma. Eur J Med Chem. 2017 Jul 28;135:49-59. doi: 10.1016/j.ejmech.2017.04.020. Epub 2017 Apr 13. Eur J Med Chem. 2017. PMID: 28431354 Free article.
Improved proteolytic stability and potent activity against Leishmania infantum trypanothione reductase of α/β-peptide foldamers conjugated to cell-penetrating peptides.
de Lucio H, Gamo AM, Ruiz-Santaquiteria M, de Castro S, Sánchez-Murcia PA, Toro MA, Gutiérrez KJ, Gago F, Jiménez-Ruiz A, Camarasa MJ, Velázquez S. de Lucio H, et al. Among authors: toro ma. Eur J Med Chem. 2017 Nov 10;140:615-623. doi: 10.1016/j.ejmech.2017.09.032. Epub 2017 Sep 21. Eur J Med Chem. 2017. PMID: 29017116 Free article.
Trypanothione reductase inhibition and anti-leishmanial activity of all-hydrocarbon stapled α-helical peptides with improved proteolytic stability.
Ruiz-Santaquiteria M, de Castro S, Toro MA, de Lucio H, Gutiérrez KJ, Sánchez-Murcia PA, Jiménez MÁ, Gago F, Jiménez-Ruiz A, Camarasa MJ, Velázquez S. Ruiz-Santaquiteria M, et al. Among authors: toro ma. Eur J Med Chem. 2018 Apr 10;149:238-247. doi: 10.1016/j.ejmech.2018.02.071. Epub 2018 Feb 24. Eur J Med Chem. 2018. PMID: 29501944 Free article.
134 results