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A computationally designed antigen eliciting broad humoral responses against SARS-CoV-2 and related sarbecoviruses.
Vishwanath S, Carnell GW, Ferrari M, Asbach B, Billmeier M, George C, Sans MS, Nadesalingam A, Huang CQ, Paloniemi M, Stewart H, Chan A, Wells DA, Neckermann P, Peterhoff D, Einhauser S, Cantoni D, Neto MM, Jordan I, Sandig V, Tonks P, Temperton N, Frost S, Sohr K, Ballesteros MTL, Arbabi F, Geiger J, Dohmen C, Plank C, Kinsley R, Wagner R, Heeney JL. Vishwanath S, et al. Among authors: tonks p. Nat Biomed Eng. 2023 Sep 25. doi: 10.1038/s41551-023-01094-2. Online ahead of print. Nat Biomed Eng. 2023. PMID: 37749309
Glycan masking of a non-neutralising epitope enhances neutralising antibodies targeting the RBD of SARS-CoV-2 and its variants.
Carnell GW, Billmeier M, Vishwanath S, Suau Sans M, Wein H, George CL, Neckermann P, Del Rosario JMM, Sampson AT, Einhauser S, Aguinam ET, Ferrari M, Tonks P, Nadesalingam A, Schütz A, Huang CQ, Wells DA, Paloniemi M, Jordan I, Cantoni D, Peterhoff D, Asbach B, Sandig V, Temperton N, Kinsley R, Wagner R, Heeney JL. Carnell GW, et al. Among authors: tonks p. Front Immunol. 2023 Feb 23;14:1118523. doi: 10.3389/fimmu.2023.1118523. eCollection 2023. Front Immunol. 2023. PMID: 36911730 Free PMC article.
Immunological insights into COVID-19 in Southern Nigeria.
Ugwu CA, Alao O, John OG, Akinnawo B, Ajayi I, Odebode O, Bejide I, Campbell A, Campbell J, Adole JA, B Olawoye I, Akano K, Okolie J, Eromon P, Olaitan P, Olagunoye A, Adebayo I, Adebayo V, Babalola E, Abioye O, Ajayi N, Ogah E, Ukwaja K, Okoro S, Oje O, Kingsley OC, Eke M, Onyia V, Achonduh-Atijegbe O, Ewah FE, Obasi M, Igwe V, Ayodeji O, Chukwuyem A, Owhin S, Oyejide N, Abah S, Ingbian W, Osoba M, Alebiosu A, Nadesalingam A, Aguinam ET, Carnell G, Krause N, Chan A, George C, Kinsley R, Tonks P, Temperton N, Heeney J, Happi C. Ugwu CA, et al. Among authors: tonks p. Front Immunol. 2024 Jan 23;15:1305586. doi: 10.3389/fimmu.2024.1305586. eCollection 2024. Front Immunol. 2024. PMID: 38322252 Free PMC article.
Humoral and cellular immune responses to Lassa fever virus in Lassa fever survivors and their exposed contacts in Southern Nigeria.
Ugwu C, Olumade T, Nwakpakpa E, Onyia V, Odeh E, Duruiheoma RO, Ojide CK, Eke MA, Nwafor IE, Chika-Igwenyi N, Abu AM, Azuogu B, Ajayi N, Ogah E, Ayodeji O, Abejegah C, Adedosu N, Oyejide N, Abah S, Omidele A, Ingbian W, Osoba E, Eromon P, Oluniyi P, Ogunsanya O, Happi A, Otuh P, Nadesalingam A, Carnell G, Krause N, Aguinam E, Kinsley R, Storisteanu DML, Tonks P, Nelson D, McAlister C, Boisen M, Garry R, Wright E, Temperton N, Frost S, Heeney JL, Happi C. Ugwu C, et al. Among authors: tonks p. Sci Rep. 2022 Dec 25;12(1):22330. doi: 10.1038/s41598-022-26045-w. Sci Rep. 2022. PMID: 36567369 Free PMC article.
Analysis of Serological Biomarkers of SARS-CoV-2 Infection in Convalescent Samples From Severe, Moderate and Mild COVID-19 Cases.
Castillo-Olivares J, Wells DA, Ferrari M, Chan ACY, Smith P, Nadesalingam A, Paloniemi M, Carnell GW, Ohlendorf L, Cantoni D, Mayora-Neto M, Palmer P, Tonks P, Temperton NJ, Peterhoff D, Neckermann P, Wagner R, Doffinger R, Kempster S, Otter AD, Semper A, Brooks T, Albecka A, James LC, Page M, Schwaeble W, Baxendale H, Heeney JL. Castillo-Olivares J, et al. Among authors: tonks p. Front Immunol. 2021 Nov 19;12:748291. doi: 10.3389/fimmu.2021.748291. eCollection 2021. Front Immunol. 2021. PMID: 34867975 Free PMC article.
Critical Care Workers Have Lower Seroprevalence of SARS-CoV-2 IgG Compared with Non-patient Facing Staff in First Wave of COVID19.
Baxendale HE, Wells D, Gronlund J, Nadesalingham A, Paloniemi M, Carnell G, Tonks P, Ceron-Gutierrez L, Ebrahimi S, Sayer A, Briggs JAG, Ziong X, Nathan JA, Grice G, James LC, Luptak J, Pai S, Heeney JL, Lear S, Doffinger R. Baxendale HE, et al. Among authors: tonks p. J Crit Care Med (Targu Mures). 2021 Aug 5;7(3):199-210. doi: 10.2478/jccm-2021-0018. eCollection 2021 Jul. J Crit Care Med (Targu Mures). 2021. PMID: 34722923 Free PMC article.
Stepwise Conformational Stabilization of a HIV-1 Clade C Consensus Envelope Trimer Immunogen Impacts the Profile of Vaccine-Induced Antibody Responses.
Hauser A, Carnell G, Held K, Sulbaran G, Tischbierek N, Rogers L, Pollakis G, Tonks P, Hoelscher M, Ding S, Sanders RW, Geldmacher C, Sattentau Q, Weissenhorn W, Heeney JL, Peterhoff D, Wagner R. Hauser A, et al. Among authors: tonks p. Vaccines (Basel). 2021 Jul 6;9(7):750. doi: 10.3390/vaccines9070750. Vaccines (Basel). 2021. PMID: 34358165 Free PMC article.
29 results